Results 331 to 340 of about 320,119 (385)

Molecular mechanisms of vancomycin resistance

open access: yesProtein Science, 2020
Vancomycin and related glycopeptides are drugs of last resort for the treatment of severe infections caused by Gram‐positive bacteria such as Enterococcus species, Staphylococcus aureus, and Clostridium difficile. Vancomycin was long considered immune to
Peter J Stogios, Alexei Savchenko
exaly   +2 more sources
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Evidence-based Guideline for Therapeutic Drug Monitoring of Vancomycin: 2020 Update by the Division of Therapeutic Drug Monitoring, Chinese Pharmacological Society.

Clinical Infectious Diseases, 2020
BACKGROUND Clinical practice guidelines or recommendations often require timely and regular updating as new evidence emerges, because this can alter the risk-benefit trade-off.
N. He   +53 more
semanticscholar   +1 more source

Vancomycin

Journal of Antimicrobial Chemotherapy, 1982
While vancomycin is thus not as nephrotoxic as once feared, its use by the parenteral route should be avoided if possible when other nephrotoxic drugs are being given. Used properly, vancomycin appears efficacious and can be given with safety to infants, children, and adults.
openaire   +4 more sources

Vancomycin

Mayo Clinic Proceedings, 1987
Vancomycin is a narrow-spectrum bactericidal antibiotic used primarily for treatment of serious staphylococcal infections. It is the alternative therapy of choice when the penicillins and cephalosporins cannot be used. Vancomycin is also used in (1) methicillin-resistant Staphylococcus aureus infections; (2) streptococcal endocarditis in conjunction ...
P E, Hermans, M P, Wilhelm
openaire   +2 more sources

Protein-inspired antibiotics active against vancomycin- and daptomycin-resistant bacteria

open access: yesNature Communications, 2018
The public health threat posed by a looming ‘post-antibiotic’ era necessitates new approaches to antibiotic discovery. Drug development has typically avoided exploitation of membrane-binding properties, in contrast to nature’s control of biological ...
Assoc prof Mark A T Blaskovich   +2 more
exaly   +2 more sources

Vancomycin Revisited

Annals of Internal Medicine, 1978
Vancomycin, virtually discarded after development of antistaphylococcal penicillins, has recently been receiving renewed attention. There are several clinical situations in which it appears to offer advantages over other available antimicrobial agents: infections due to methicillin-resistant staphylococci; bacterial endocarditis in patients allergic to
F V, Cook, W E, Farrar
openaire   +2 more sources

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