Results 201 to 210 of about 98,361 (266)

Facial expression recognition via variational inference. [PDF]

Sci Rep
Lv G, Zhang J, Tsoi C.
europepmc   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Cattle production drives agricultural energy intensity and greenhouse gas emissions in Latin America and the Caribbean. [PDF]

Sci Rep
Mejía D, Junca Paredes JJ, Burkart S.
europepmc   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Bidirectional temporal relationships between emotional state and eating across eating disorders: a network approach. [PDF]

J Eat Disord
Kahveci S, Reichenberger J, Arend AK, Mansueto AC, Freichel R, Voderholzer U, Blechert J.   +6 more
europepmc   +1 more source

Optimization of the extraction process and <i>in vitro</i> antioxidant capacity analysis of selenium-containing proteins from <i>Cynanchum thesioides</i>. [PDF]

PeerJ
Men Y, Han X, Huang X, Zhang X, Wei P, Yang Z, Zhang F.   +6 more
europepmc   +1 more source

Comparative Evaluation of Optical Alignment Algorithms for Integrated Probe Cards in Photonic Wafer Testing. [PDF]

Micromachines (Basel)
Bejani M, Galli A, Vettori R, Mauri M, Mariani S.   +4 more
europepmc   +1 more source

Mechanistic insights into coordinated var transcriptional switching in malaria parasites. [PDF]

EMBO J
Visone JE, Florini F, Hadjimichael E, Patel V, Deitsch KW.   +4 more
europepmc   +1 more source