Results 1 to 10 of about 9,382 (159)

The Antiviral Activity of Varenicline against Dengue Virus Replication during the Post-Entry Stage [PDF]

Biomedicines, 2023
Dengue virus (DENV) poses a significant global health challenge, with millions of cases each year. Developing effective antiviral drugs against DENV remains a major hurdle. Varenicline is a medication used to aid smoking cessation, with anti-inflammatory
Ching-Lin Lin, Yan-Tung Kiu, Ju-Ying Kan, Yu-Jen Chang, Ping-Yi Hung, Chih-Hao Lu, Wen-Ling Lin, Yow-Wen Hsieh, Jung-Yie Kao, Nien-Jen Hu, Cheng-Wen Lin   +10 more
doaj   +2 more sources

Visual hallucinations associated with varenicline: a case report [PDF]

Journal of Medical Case Reports, 2009
Introduction Varenicline is widely used for smoking cessation. It has shown efficacy over placebo and bupropion in manufacturer-sponsored trials. Those with mental illness were excluded from these trials.
Raidoo B Mahendri, Kutscher Eric C
doaj   +2 more sources

Characteristics of first-time varenicline users – A cross-sectional study in Finnish quitters [PDF]

BMC Public Health, 2017
Background Varenicline is an efficacious medicine for smoking cessation (SC) but little is known about the characteristics of varenicline users. This study examined the characteristics of first-time (naïve) varenicline users in Finland and compared those
Hanna E. Tervonen, Juha H. O. Turunen, Christine L. Baker, Juha Laine, Kari Linden   +4 more
doaj   +2 more sources

Hesperidin blocks varenicline-aggravated atherosclerotic plaque formation in apolipoprotein E knockout mice by downregulating net uptake of oxidized low-density lipoprotein in macrophages

Journal of Pharmacological Sciences, 2020
Varenicline is a widely used and effective drug for smoking cessation. We have previously reported experimental evidence suggesting that varenicline increases the risk of cardiovascular events.
Mitsuhisa Koga, Yuki Kanaoka, Koshun Inada, Sai Omine, Yasufumi Kataoka, Atsushi Yamauchi   +5 more
doaj   +2 more sources

Utilization of varenicline among Kansas Medicaid enrollees. [PDF]

PLoS ONE
BackgroundSmoking prevalence among Medicaid beneficiaries is twice that of privately insured adults, yet effective smoking cessation treatments remain underutilized.
Nathalia M Machado, Aaron J Katz, Kimber P Richter, Edward F Ellerbeck   +3 more
doaj   +2 more sources

Use of low-dose varenicline in hospitalized smokers: A case series low-dose varenicline in hospitalized smokers [PDF]

SAGE Open Medical Case Reports
Nicotine replacement therapy is the primary medication used to treat tobacco dependence in hospitalized patients. Recent evidence shows that varenicline is more effective than nicotine replacement, but varenicline side effects limit its use in the ...
Rachael L. Joyner, Remi E. Phillips, Farid A. Manshaii, James M. Davis   +3 more
doaj   +2 more sources

Exposure to varenicline protects against locomotor alteration in a MPTP mouse model of Parkinson's disease

Brazilian Journal of Medical and Biological Research, 2021
The beneficial effects of drugs that act via nicotinic acetylcholine receptors (nAChRs) on Parkinson's disease (PD) symptomatology may explain the negative correlation between cigarette smoking and risk of this neurological condition.
A. Ribeiro-Carvalho, P.H. Leal-Rocha, J. Isnardo-Fernandes, U.C. Araújo, Y. Abreu-Villaça, C.C. Filgueiras, A.C. Manhães   +6 more
doaj   +1 more source

Pharmacovigilance Study on Adverse Events of Nicotine Replacement Therapy, Bupropion, and Varenicline in Patients with Chronic Obstructive Pulmonary Disease. [PDF]

Int J Chron Obstruct Pulmon Dis
Wang YD, Wang YT, Chen HH, Bao JK, Chen SM, Chen DX.   +5 more
europepmc   +3 more sources

Efficacy of varenicline versus bupropion for smoking cessation: A systematic review and meta-analysis of randomized controlled trials

Indian Journal of Psychiatry, 2023
According to the Global Burden of Disease (GBD) Study conducted in 2019, smoking tobacco leads to over 8 million deaths each year. Hence, it is crucial to identify optimal smoking cessation therapy. To compare the efficacy of varenicline versus bupropion
Ashish R. Patel, Jigar R. Panchal, Chetna K. Desai   +2 more
doaj   +1 more source

Varenicline aggravates atherosclerotic plaque formation in nicotine-pretreated ApoE knockout mice due to enhanced oxLDL uptake by macrophages through downregulation of ABCA1 and ABCG1 expression

Journal of Pharmacological Sciences, 2020
Varenicline is a widely used and effective drug for smoking cessation. We previously reported that varenicline aggravates atherosclerosis in apolipoprotein E knockout (ApoE KO) mice.
Mitsuhisa Koga, Yuki Kanaoka, Mana Okamoto, Yuki Nakao, Koshun Inada, Saki Takayama, Yasufumi Kataoka, Atsushi Yamauchi   +7 more
doaj   +1 more source