Results 1 to 10 of about 15,047 (197)
Study protocol for a randomised controlled trial of electronic cigarettes versus nicotine patch for smoking cessation [PDF]
PMCID: PMC3602285This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided ...
Bullen, C +6 more
core +1 more source
GLP‐1 at the Metabolic–Cognitive Interface: Reward, Affect, and Memory
GLP‐1R signaling integrates metabolic state with neural circuits controlling reward, mood, and memory, acting as a metabolic‐cognitive interface. In reward pathways, it suppresses hedonic feeding and drug seeking; in affective circuits, sustained signaling promotes anxiolytic and antidepressant effects; and in the hippocampus, it enhances synaptic ...
Serena X. Gao +5 more
wiley +1 more source
Nicotine dependence and neuropsychotic effects of varenicline
Varenicline is a partial agonist of nicotinic acetylcholine receptors for the therapy of nicotine addiction. The efficacy and safety of the use of varenicline in the treatment of nicotine dependence have been demonstrated in clinical trial EAGLES.
T. M. Bukatina +4 more
doaj +1 more source
The cost-effectiveness of smoking cessation support delivered by mobile phone text messaging: Txt2stop. [PDF]
BACKGROUND: The txt2stop trial has shown that mobile-phone-based smoking cessation support doubles biochemically validated quitting at 6 months. This study examines the cost-effectiveness of smoking cessation support delivered by mobile phone text ...
Cairns, John +5 more
core +2 more sources
ABSTRACT Background and Aims Diabetes mellitus is a chronic endocrine disorder requiring long‐term medication therapy. In addition to medication therapy, appropriate diabetes self‐care activities are crucial for the management and prevention of complications of diabetes mellitus. The study aims to investigate diabetes self‐care activity and explore its
Sonu Neupane +5 more
wiley +1 more source
The data shows attentional function, impulsivity, motivation, motor function, and motor activity in rats treated with varenicline, a stop-smoking aid.
Yu Ohmura +5 more
doaj +1 more source
Use of varenicline for smoking cessation treatment in UK primary care: an association rule mining analysis [PDF]
BACKGROUND: Varenicline is probably the most effective smoking cessation pharmacotherapy, but is less widely used than nicotine replacement therapy. We therefore set out to identify the characteristics of numerically important groups of patients who ...
Action on Smoking and Health (ASH) +24 more
core +3 more sources
Varenicline for smoking cessation: efficacy, safety, and treatment recommendations
Jon O Ebbert, Kirk D Wyatt, J Taylor Hays, Eric W Klee, Richard D HurtMayo Clinic College of Medicine, Rochester, MN, USAAbstract: Smoking is the leading preventable cause of morbidity and mortality in the US, and decreasing smoking prevalence is a ...
Jon O Ebbert +3 more
doaj
OBJECTIVES/SPECIFIC AIMS: The central goal is to predict the metabolites of varenicline and predictively evaluate their propensities for eliciting an increased binding effect in the brain.
Keeshaloy Thompson, Milton Brown
doaj +1 more source
Differentiating the primary reinforcing and reinforcement-enhancing effects of varenicline in a 2-lever, rat self-administration paradigm [PDF]
Nicotine (NIC) has two reinforcement-related effects that may contribute to dependence: 1) NIC acts as a primary reinforcer, and 2) NIC, non-associatively, enhances reinforcement from concur- rently available nonpharmacological stimuli. Varenicline (VAR),
Levin, Melissa
core

