Results 1 to 10 of about 15,047 (197)

Study protocol for a randomised controlled trial of electronic cigarettes versus nicotine patch for smoking cessation [PDF]

open access: yes, 2013
PMCID: PMC3602285This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided ...
Bullen, C   +6 more
core   +1 more source

GLP‐1 at the Metabolic–Cognitive Interface: Reward, Affect, and Memory

open access: yesComprehensive Physiology, Volume 16, Issue 2, April 2026.
GLP‐1R signaling integrates metabolic state with neural circuits controlling reward, mood, and memory, acting as a metabolic‐cognitive interface. In reward pathways, it suppresses hedonic feeding and drug seeking; in affective circuits, sustained signaling promotes anxiolytic and antidepressant effects; and in the hippocampus, it enhances synaptic ...
Serena X. Gao   +5 more
wiley   +1 more source

Nicotine dependence and neuropsychotic effects of varenicline

open access: yesБезопасность и риск фармакотерапии, 2018
Varenicline is a partial agonist of nicotinic acetylcholine receptors for the therapy of nicotine addiction. The efficacy and safety of the use of varenicline in the treatment of nicotine dependence have been demonstrated in clinical trial EAGLES.
T. M. Bukatina   +4 more
doaj   +1 more source

The cost-effectiveness of smoking cessation support delivered by mobile phone text messaging: Txt2stop. [PDF]

open access: yes, 2012
BACKGROUND: The txt2stop trial has shown that mobile-phone-based smoking cessation support doubles biochemically validated quitting at 6 months. This study examines the cost-effectiveness of smoking cessation support delivered by mobile phone text ...
Cairns, John   +5 more
core   +2 more sources

Evaluation of Diabetes Self‐Care Activities and Glycemic Control Profiles in People With Type 2 Diabetes Mellitus

open access: yesHealth Science Reports, Volume 9, Issue 4, April 2026.
ABSTRACT Background and Aims Diabetes mellitus is a chronic endocrine disorder requiring long‐term medication therapy. In addition to medication therapy, appropriate diabetes self‐care activities are crucial for the management and prevention of complications of diabetes mellitus. The study aims to investigate diabetes self‐care activity and explore its
Sonu Neupane   +5 more
wiley   +1 more source

The data set describing cognitive performance after varenicline administration in a 3-choice serial reaction time task in rats

open access: yesData in Brief, 2017
The data shows attentional function, impulsivity, motivation, motor function, and motor activity in rats treated with varenicline, a stop-smoking aid.
Yu Ohmura   +5 more
doaj   +1 more source

Use of varenicline for smoking cessation treatment in UK primary care: an association rule mining analysis [PDF]

open access: yes, 2014
BACKGROUND: Varenicline is probably the most effective smoking cessation pharmacotherapy, but is less widely used than nicotine replacement therapy. We therefore set out to identify the characteristics of numerically important groups of patients who ...
Action on Smoking and Health (ASH)   +24 more
core   +3 more sources

Varenicline for smoking cessation: efficacy, safety, and treatment recommendations

open access: yesPatient Preference and Adherence, 2010
Jon O Ebbert, Kirk D Wyatt, J Taylor Hays, Eric W Klee, Richard D HurtMayo Clinic College of Medicine, Rochester, MN, USAAbstract: Smoking is the leading preventable cause of morbidity and mortality in the US, and decreasing smoking prevalence is a ...
Jon O Ebbert   +3 more
doaj  

2532

open access: yesJournal of Clinical and Translational Science, 2017
OBJECTIVES/SPECIFIC AIMS: The central goal is to predict the metabolites of varenicline and predictively evaluate their propensities for eliciting an increased binding effect in the brain.
Keeshaloy Thompson, Milton Brown
doaj   +1 more source

Differentiating the primary reinforcing and reinforcement-enhancing effects of varenicline in a 2-lever, rat self-administration paradigm [PDF]

open access: yes, 2013
Nicotine (NIC) has two reinforcement-related effects that may contribute to dependence: 1) NIC acts as a primary reinforcer, and 2) NIC, non-associatively, enhances reinforcement from concur- rently available nonpharmacological stimuli. Varenicline (VAR),
Levin, Melissa
core  

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