Results 1 to 10 of about 20,063 (249)

The Antiviral Activity of Varenicline against Dengue Virus Replication during the Post-Entry Stage [PDF]

open access: goldBiomedicines, 2023
Dengue virus (DENV) poses a significant global health challenge, with millions of cases each year. Developing effective antiviral drugs against DENV remains a major hurdle. Varenicline is a medication used to aid smoking cessation, with anti-inflammatory
Ching-Lin Lin   +10 more
doaj   +3 more sources

Effect of Extending the Duration of Prequit Treatment With Varenicline on Smoking Abstinence [PDF]

open access: goldJAMA Network Open, 2022
Key Points Question Does extending the duration of prequit treatment with varenicline improve rates of smoking abstinence? Findings In this randomized clinical trial that included 320 adults, the percentage of bioverified continuous 4-week abstinence ...
Larry W. Hawk   +7 more
openalex   +2 more sources

Varenicline Prevents LPS-Induced Inflammatory Response via Nicotinic Acetylcholine Receptors in RAW 264.7 Macrophages

open access: yesFrontiers in Molecular Biosciences, 2021
The cholinergic anti-inflammatory pathway plays an important role in controlling inflammation. This study investigated the effects of varenicline, an α7 nicotinic acetylcholine receptor (α7nAChR) agonist, on inflammatory cytokine levels, cell ...
Elif Baris   +5 more
doaj   +2 more sources

Visual hallucinations associated with varenicline: a case report [PDF]

open access: goldJournal of Medical Case Reports, 2009
Introduction Varenicline is widely used for smoking cessation. It has shown efficacy over placebo and bupropion in manufacturer-sponsored trials. Those with mental illness were excluded from these trials.
Raidoo B Mahendri, Kutscher Eric C
doaj   +2 more sources

Exposure to varenicline protects against locomotor alteration in a MPTP mouse model of Parkinson's disease

open access: yesBrazilian Journal of Medical and Biological Research, 2021
The beneficial effects of drugs that act via nicotinic acetylcholine receptors (nAChRs) on Parkinson's disease (PD) symptomatology may explain the negative correlation between cigarette smoking and risk of this neurological condition.
A. Ribeiro-Carvalho   +6 more
doaj   +2 more sources

Characteristics of first-time varenicline users – A cross-sectional study in Finnish quitters [PDF]

open access: goldBMC Public Health, 2017
Background Varenicline is an efficacious medicine for smoking cessation (SC) but little is known about the characteristics of varenicline users. This study examined the characteristics of first-time (naïve) varenicline users in Finland and compared those
Hanna E. Tervonen   +4 more
doaj   +2 more sources

Hesperidin blocks varenicline-aggravated atherosclerotic plaque formation in apolipoprotein E knockout mice by downregulating net uptake of oxidized low-density lipoprotein in macrophages

open access: goldJournal of Pharmacological Sciences, 2020
Varenicline is a widely used and effective drug for smoking cessation. We have previously reported experimental evidence suggesting that varenicline increases the risk of cardiovascular events.
Mitsuhisa Koga   +5 more
doaj   +2 more sources

Neuropsychiatric safety of varenicline in the general and COPD population with and without psychiatric disorders: a retrospective cohort study in a real-world setting

open access: yesBMJ Open, 2021
Objectives To evaluate the real-world association between varenicline and neuropsychiatric adverse events (NPAEs) in general and chronic obstructive pulmonary disease (COPD) population with and without psychiatric disorders compared with nicotine ...
Yuanyuan Wang   +6 more
doaj   +2 more sources

Effects of varenicline on sympatho-vagal balance and cue reactivity during smoking withdrawal: a randomised placebo-controlled trial [PDF]

open access: yesTobacco Induced Diseases, 2016
Introduction Varenicline is an effective smoking cessation medication. Some concern has been raised that its use may precipitate adverse cardiovascular events although no patho-physiological mechanism potentially underlying such an effect has been ...
Helge Haarmann   +7 more
doaj   +3 more sources

Home - About - Disclaimer - Privacy