Structural differences determine the relative selectivity of nicotinic compounds for native α4β2^*-, α6β2^*-, α3β4^*- and α7-nicotine acetylcholine receptors [PDF]
, 2010 Mammalian brain expresses multiple nicotinic acetylcholine receptor (nAChR) subtypes that differ in subunit composition, sites of expression and pharmacological and functional properties.
Bencherif, Merouane +10 more
core
The neurobiological basis for partial agonist treatment of nicotine dependence: varenicline
, 2006 Jonathan Foulds
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Cost-effectiveness of varenicline compared with nicotine patches for smoking cessation—results from four European countries [PDF]
, 2009 Kristian Bolin +6 more
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Varenicline has antidepressant-like activity in the forced swim test and augments sertraline's effect [PDF]
, 2009 Hans Rollema +6 more
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Leading Causes of Death in Vietnam [PDF]
, 2017 Vietnam is currently facing a public health crisis. Rates of chronic and preventable diseases are climbing, in addition to mortality rates from these diseases.
Roth, Lindsey
core +1 more source
Varenicline attenuates nicotine-enhanced brain-stimulation reward by activation of α4β2 nicotinic receptors in rats [PDF]
, 2009 Krista J. Spiller +6 more
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Binding Interactions with the Complementary Subunit of Nicotinic Receptors [PDF]
, 2013 The agonist-binding site of nicotinic acetylcholine receptors (nAChRs) spans an interface between two subunits of the pentameric receptor. The principal component of this binding site is contributed by an α subunit, and it binds the cationic moiety of ...
Blum, Angela P. +4 more
core
Which smoking cessation interventions work best? [PDF]
, 2011 Nicotine replacement therapy (NRT), bupropion, nortriptyline, clonidine, and varenicline are all effective, although insufficient evidence exists to recommend one intervention over another (SOR: A, systematic reviews).
Flake, Donna +4 more
core
Varenicline and P50 auditory gating in medicated schizophrenic patients: A pilot study [PDF]
, 2009 Merilyne C. Waldo +2 more
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Varenicline improved laparotomy-induced cognitive impairment by restoring mitophagy in aged mice.
European Journal of Pharmacology, 2021 Jianan Wang +10 more
semanticscholar +1 more source