Results 21 to 30 of about 20,079 (290)

Varenicline aggravates atherosclerotic plaque formation in nicotine-pretreated ApoE knockout mice due to enhanced oxLDL uptake by macrophages through downregulation of ABCA1 and ABCG1 expression

Journal of Pharmacological Sciences, 2020
Varenicline is a widely used and effective drug for smoking cessation. We previously reported that varenicline aggravates atherosclerosis in apolipoprotein E knockout (ApoE KO) mice.
Mitsuhisa Koga, Yuki Kanaoka, Mana Okamoto, Yuki Nakao, Koshun Inada, Saki Takayama, Yasufumi Kataoka, Atsushi Yamauchi   +7 more
doaj   +1 more source

Varenicline Solution Nasal Spray: A Review in Dry Eye Disease

Drugs, 2022
Increasing endogenous tear film production via pharmacological neuroactivation of the nasolacrimal reflex [NLR; also known as the trigeminal parasympathetic pathway (TPP)] is a novel therapeutic approach to treating dry eye disease (DED).
J. Frampton
semanticscholar   +1 more source

Effect of Cytisine vs Varenicline on Smoking Cessation: A Randomized Clinical Trial.

Journal of the American Medical Association (JAMA), 2021
Importance Cytisine is more effective than placebo and nicotine replacement therapy for smoking cessation. However, cytisine has not been tested against the most effective smoking cessation medication, varenicline, which is associated with adverse events
R. Courtney, H. McRobbie, P. Tutka, Natasha Weaver, D. Petrie, C. Mendelsohn, A. Shakeshaft, Saki Talukder, Christel Macdonald, D. Thomas, Benjamin Kwan, Natalie Walker, C. Gartner, R. Mattick, C. Paul, S. G. Ferguson, N. Zwar, R. Richmond, C. Doran, Veronica C. Boland, W. Hall, R. West, M. Farrell   +22 more
semanticscholar   +1 more source

Effectiveness of Varenicline and Cytisine for Alcohol Use Reduction Among People With HIV and Substance Use

JAMA Network Open, 2022
This randomized clinical trial compares the effectiveness of varenicline and cytisine with nicotine replacement therapy for reducing alcohol consumption among individuals with HIV who smoke daily and engage in risky drinking.
H. Tindle, M. Freiberg, D. Cheng, N. Gnatienko, E. Blokhina, T. Yaroslavtseva, S. Bendiks, G. Patts, J. Hahn, K. So-Armah, M. Stein, K. Bryant, D. Lioznov, E. Krupitsky, J. Samet   +14 more
semanticscholar   +1 more source

Effect of Combination Treatment With Varenicline and Nicotine Patch on Smoking Cessation Among Smokers Who Drink Heavily

JAMA Network Open, 2022
Key Points Question Is the combination of varenicline tartrate and nicotine patch a more effective treatment than placebo with nicotine patch for smoking cessation in adult cigarette smokers who drink heavily?
Andrea King, Ashley Vena, H. de Wit, J. Grant, Dingcai Cao   +4 more
semanticscholar   +1 more source

Hesperidin blocks varenicline-aggravated atherosclerotic plaque formation in apolipoprotein E knockout mice by downregulating net uptake of oxidized low-density lipoprotein in macrophages

Journal of Pharmacological Sciences, 2020
Varenicline is a widely used and effective drug for smoking cessation. We have previously reported experimental evidence suggesting that varenicline increases the risk of cardiovascular events.
Mitsuhisa Koga, Yuki Kanaoka, Koshun Inada, Sai Omine, Yasufumi Kataoka, Atsushi Yamauchi   +5 more
doaj   +1 more source

E-cigarettes to Augment Stop Smoking In-person Support and Treatment With Varenicline (E-ASSIST): A Pragmatic Randomized Controlled Trial

Nicotine & Tobacco Research, 2022
Aim To examine whether, in adults receiving behavioral support, offering e-cigarettes together with varenicline helps more people stop smoking cigarettes than varenicline alone. Methods A two-group, parallel arm, pragmatic randomized controlled trial was
Harry Tattan-Birch, L. Kock, Jamie Brown, E. Beard, L. Bauld, R. West, L. Shahab   +6 more
semanticscholar   +1 more source

Effect of Varenicline Added to Counseling on Smoking Cessation Among African American Daily Smokers: The Kick It at Swope IV Randomized Clinical Trial.

Journal of the American Medical Association (JAMA), 2022
Importance African American smokers have among the highest rates of tobacco-attributable morbidity and mortality in the US, and effective treatment is needed for all smoking levels.
L. Cox, Nicole L. Nollen, M. Mayo, B. Faseru, A. Greiner, E. Ellerbeck, R. Krebill, R. Tyndale, N. Benowitz, J. Ahluwalia   +9 more
semanticscholar   +1 more source

Efficacy and Safety of Varenicline for Smoking Cessation in Patients With Type 2 Diabetes

JAMA Network Open, 2022
This randomized clinical trial examines the effect of smoking cessation medication and counseling in smokers with type 2 diabetes.
C. Russo, Magdalena Walicka, P. Caponnetto, F. Cibella, Marilena Maglia, A. Alamo, D. Campagna, L. Frittitta, Maurizio Di Mauro, G. Caci, A. Krysiński, E. Franek, R. Polosa   +12 more
semanticscholar   +1 more source

Integration of Tobacco Treatment Services into Cancer Care at Stanford. [PDF]

, 2020
As part of a National Cancer Institute Moonshot P30 Supplement, the Stanford Cancer Center piloted and integrated tobacco treatment into cancer care. This quality improvement (QI) project reports on the process from initial pilot to adoption within 14 ...
Fielding-Singh, Priya, Gali, Kathleen, Jimenez, Kayla, Kendra, Matthew S, Mirkin, Rachelle, Pike, Brittany, Prochaska, Judith J, Tran, Cindy   +7 more
core   +2 more sources