Results 21 to 30 of about 20,263 (262)

Efficacy of Varenicline in the Treatment of Alcohol Dependence: An Updated Meta-Analysis and Meta-Regression

open access: yesInternational Journal of Environmental Research and Public Health, 2023
Background: Although varenicline has been used for alcohol dependence (AD) treatment, its efficacy for this condition remains controversial. Aims: This systematic review and meta-analysis of randomized controlled trials (RCTs) assesses the efficacy and ...
Wiraphol Phimarn   +4 more
semanticscholar   +1 more source

Association of the Chantix Recall With US Prescribing of Varenicline and Other Medications for Nicotine Dependence

open access: yesJAMA Network Open, 2023
This cross-sectional study evaluates the association between the 2021 varenicline tartrate recall and prescribing of varenicline and other medications for nicotine dependence in a large US national patient cohort.
A. E. Lang   +5 more
semanticscholar   +1 more source

Varenicline aggravates atherosclerotic plaque formation in nicotine-pretreated ApoE knockout mice due to enhanced oxLDL uptake by macrophages through downregulation of ABCA1 and ABCG1 expression

open access: yesJournal of Pharmacological Sciences, 2020
Varenicline is a widely used and effective drug for smoking cessation. We previously reported that varenicline aggravates atherosclerosis in apolipoprotein E knockout (ApoE KO) mice.
Mitsuhisa Koga   +7 more
doaj   +1 more source

Varenicline Solution Nasal Spray: A Review in Dry Eye Disease

open access: yesDrugs, 2022
Increasing endogenous tear film production via pharmacological neuroactivation of the nasolacrimal reflex [NLR; also known as the trigeminal parasympathetic pathway (TPP)] is a novel therapeutic approach to treating dry eye disease (DED).
J. Frampton
semanticscholar   +1 more source

Effect of Cytisine vs Varenicline on Smoking Cessation: A Randomized Clinical Trial.

open access: yesJournal of the American Medical Association (JAMA), 2021
Importance Cytisine is more effective than placebo and nicotine replacement therapy for smoking cessation. However, cytisine has not been tested against the most effective smoking cessation medication, varenicline, which is associated with adverse events
R. Courtney   +22 more
semanticscholar   +1 more source

Effectiveness of Varenicline and Cytisine for Alcohol Use Reduction Among People With HIV and Substance Use

open access: yesJAMA Network Open, 2022
This randomized clinical trial compares the effectiveness of varenicline and cytisine with nicotine replacement therapy for reducing alcohol consumption among individuals with HIV who smoke daily and engage in risky drinking.
H. Tindle   +14 more
semanticscholar   +1 more source

E-cigarettes to Augment Stop Smoking In-person Support and Treatment With Varenicline (E-ASSIST): A Pragmatic Randomized Controlled Trial

open access: yesNicotine & Tobacco Research, 2022
Aim To examine whether, in adults receiving behavioral support, offering e-cigarettes together with varenicline helps more people stop smoking cigarettes than varenicline alone. Methods A two-group, parallel arm, pragmatic randomized controlled trial was
Harry Tattan-Birch   +6 more
semanticscholar   +1 more source

Neuropsychiatric safety of varenicline in the general and COPD population with and without psychiatric disorders: a retrospective cohort study in a real-world setting

open access: yesBMJ Open, 2021
Objectives To evaluate the real-world association between varenicline and neuropsychiatric adverse events (NPAEs) in general and chronic obstructive pulmonary disease (COPD) population with and without psychiatric disorders compared with nicotine ...
Yuanyuan Wang   +6 more
doaj   +1 more source

Effect of Combination Treatment With Varenicline and Nicotine Patch on Smoking Cessation Among Smokers Who Drink Heavily

open access: yesJAMA Network Open, 2022
Key Points Question Is the combination of varenicline tartrate and nicotine patch a more effective treatment than placebo with nicotine patch for smoking cessation in adult cigarette smokers who drink heavily?
Andrea King   +4 more
semanticscholar   +1 more source

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