Results 21 to 30 of about 16,753 (223)

Is a combination of varenicline and nicotine patch more effective in helping smokers quit than varenicline alone? A randomised controlled trial [PDF]

, 2013
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work ...
A McEwen, AC Farley, Al-Rehan Dhanji, D Gonzales, DE Jorenby, H McRobbie, Hayden McRobbie, HJ Aubin, JA Stapleton, JJ Prochaska, JO Ebbert, K Cahill, Katie Myers Smith, L Bauld, LF Stead, MC Fiore, N Lindson, P Hajek, P Hajek, Peter Hajek, R West, R West, R West, S Shiffman, S Shiffman, T Health, TF Heatherton   +26 more
core   +2 more sources

The effectiveness, safety and cost-effectiveness of cytisine versus varenicline for smoking cessation in an Australian population: a study protocol for a randomized controlled non-inferiority trial [PDF]

, 2019
Smoking cessation medications are effective but often underutilised because of costs and side effects. Cytisine is a plant-based smoking cessation medication with over 50 years of use in Central and Eastern Europe.
Boland, Veronica C., Courtney, Ryan J., Doran, Christopher M., Farrell, Michael, Ferguson, Stuart G., Gartner, Coral, Hall, Wayne, Mattick, Richard P., McRobbie, Hayden, Mendelsohn, Colin P., Paul, Christine, Petrie, Dennis, Richmond, Robyn, Shakeshaft, Anthony, Siahpush, Mohammad, Thomas, Dennis, Tutka, Piotr, Walker, Natalie, West, Robert, Zwar, Nicholas   +19 more
core   +1 more source

Varenicline and Risk of Self-Harm: A Nested Case-Control Study. [PDF]

PLoS ONE, 2016
BACKGROUND:Smoking remains a serious public health concern. Pharmacotherapy for smoking cessation, including bupropion and varenicline, are proven means to increase quit rates.
Mina Tadrous, Diana Martins, Zhan Yao, Muhammad M Mamdani, David N Juurlink, Tara Gomes, Tony Antoniou   +6 more
doaj   +1 more source

Implementation of a quality improvement project on smoking cessation reduces smoking in a high risk trauma patient population. [PDF]

, 2016
BackgroundCigarette smoking causes about one of every five deaths in the U.S. each year. In 2013 the prevalence of smoking in our institution's trauma population was 26.7 %, well above the national adult average of 18.1 % according to the CDC website. As
Carrens, Karen, Doben, Andrew, Gross, Ronald, Korntner, Samuel, Nahmias, Jeffry, Poola, Shiva   +5 more
core   +1 more source

A case report on varenicline induced delirium in an alcohol and nicotine dependent patient

Indian Journal of Psychological Medicine, 2015
Varenicline is a smoking cessation agent. Varenicline acts as a partial agonist of α4β2 neuronal nicotinic acetylcholine receptor and prevents nicotine binding to the same.
A Lakshmi Narayan, H S Virupaksha, G Thejaswi, G R Saraswathy, V Madhavan, Murali Thyloth   +5 more
doaj   +1 more source

Varenicline Effects on Smoking, Cognition, and Psychiatric Symptoms in Schizophrenia: A Double-Blind Randomized Trial. [PDF]

PLoS ONE, 2016
UNLABELLED:Schizophrenic patients have a high rate of smoking and cognitive deficits which may be related to a decreased number or responsiveness of nicotinic receptors in their brains.
Robert C Smith, Revital Amiaz, Tian-Mei Si, Lawrence Maayan, Hua Jin, Sylvia Boules, Henry Sershen, Chunbo Li, Juanjuan Ren, Yanhong Liu, Mary Youseff, Abel Lajtha, Alessandro Guidotti, Mark Weiser, John M Davis   +14 more
doaj   +1 more source

Nicotine-replacement therapy: A proven treatment for smoking cessation [PDF]

, 2010
Smoking is a major cause of cardiovascular diseases, respiratory diseases and cancer. Despite the high prevalence of smokers worldwide, smokers are often neglected and not offered effective assistance with quitting their habits. In order to overcome this
Robson, Noorzurani
core   +1 more source

Use of varenicline and nicotine replacement therapy in people with and without general practitioner-recorded dementia: retrospective cohort study of routine electronic medical records

BMJ Open, 2019
Objectives Our primary objective was to estimate smoking prevalence and prescribing rates of varenicline and nicotine replacement therapy (NRT) in people with and without general practitioner (GP)-recorded dementia.
Amy Taylor, Tim Jones, Taha Itani, Richard Martin, Gemma Taylor, Kyla Thomas, Neil Davies   +6 more
doaj   +1 more source

Varenicline Interactions at the 5-HT3 Receptor Ligand Binding Site are Revealed by 5-HTBP. [PDF]

, 2015
Cys-loop receptors are the site of action of many therapeutic drugs. One of these is the smoking cessation agent varenicline, which has its major therapeutic effects at nicotinic acetylcholine (nACh) receptors but also acts at 5-HT3 receptors.
Lillestol, Reidun K, Lummis, Sarah CR, Price, Kerry L, Ulens, Chris   +3 more
core   +3 more sources

Varenicline is a smoking cessation drug that blocks alveolar expansion in mice intratracheally administrated porcine pancreatic elastase

Journal of Pharmacological Sciences, 2018
Smoking cessation is the most effective treatment in patients with emphysema and lung inflammation. The aim of the present study was to examine the effect of varenicline, a smoking cessation drug, on emphysema in porcine pancreatic elastase (PPE)-inhaled
Mitsuhisa Koga, Yuki Kanaoka, Tetsushi Tashiro, Nagisa Hashidume, Yasufumi Kataoka, Atsushi Yamauchi   +5 more
doaj   +1 more source