Results 31 to 40 of about 19,681 (252)

ONSET-1 Phase 2b Randomized Trial to Evaluate the Safety and Efficacy of OC-01 (Varenicline Solution) Nasal Spray on Signs and Symptoms of Dry Eye Disease

Cornea, 2021
Supplemental Digital Content is Available in the Text. Purpose: The purpose of this trial was to evaluate the safety and efficacy of OC-01 (varenicline solution), a nicotinic acetylcholine receptor agonist nasal spray, on signs and symptoms of dry eye ...
David L Wirta, G. Torkildsen, Blair Boehmer, D. Hollander, Edward Bendert, Lijuan Zeng, Michael Ackermann, J. Nau   +7 more
semanticscholar   +1 more source

Impact of the disruption in supply of varenicline since 2021 on smoking cessation in England: A population study. [PDF]

Addiction
Background and aims Varenicline is one of the most effective smoking cessation treatments. Its supply in England was disrupted in July 2021 due to nitrosamine impurities found by its supplier, Pfizer.
Jackson SE, Brown J, Tattan-Birch H, Shahab L.   +3 more
europepmc   +2 more sources

Nicotine addiction : a review [PDF]

, 2013
Nicotine, the major psychoactive compound in tobacco, acts as a potent addictive drug in humans. The addictive nature of nicotine leads to more than 6 million deaths a year.
Di Giovanni, Giuseppe, Vella, Jacob
core   +1 more source

Efficacy of Combining Varenicline and Naltrexone for Smoking Cessation and Drinking Reduction: A Randomized Clinical Trial.

American Journal of Psychiatry, 2021
OBJECTIVE Pharmacological treatments that can concomitantly address cigarette smoking and heavy drinking stand to improve health care delivery for these highly prevalent co-occurring conditions.
L. Ray, ReJoyce Green, Craig K. Enders, A. Leventhal, E. Grodin, Gang Li, Aaron C. Lim, E. Hartwell, A. Venegas, Lindsay R Meredith, Steven J. Nieto, S. Shoptaw, Diana Ho, K. Miotto   +13 more
semanticscholar   +1 more source

A case report on varenicline induced delirium in an alcohol and nicotine dependent patient

Indian Journal of Psychological Medicine, 2015
Varenicline is a smoking cessation agent. Varenicline acts as a partial agonist of α4β2 neuronal nicotinic acetylcholine receptor and prevents nicotine binding to the same.
A Lakshmi Narayan, H S Virupaksha, G Thejaswi, G R Saraswathy, V Madhavan, Murali Thyloth   +5 more
doaj   +1 more source

Varenicline Effects on Smoking, Cognition, and Psychiatric Symptoms in Schizophrenia: A Double-Blind Randomized Trial. [PDF]

PLoS ONE, 2016
UNLABELLED:Schizophrenic patients have a high rate of smoking and cognitive deficits which may be related to a decreased number or responsiveness of nicotinic receptors in their brains.
Robert C Smith, Revital Amiaz, Tian-Mei Si, Lawrence Maayan, Hua Jin, Sylvia Boules, Henry Sershen, Chunbo Li, Juanjuan Ren, Yanhong Liu, Mary Youseff, Abel Lajtha, Alessandro Guidotti, Mark Weiser, John M Davis   +14 more
doaj   +1 more source

Integration of Tobacco Treatment Services into Cancer Care at Stanford. [PDF]

, 2020
As part of a National Cancer Institute Moonshot P30 Supplement, the Stanford Cancer Center piloted and integrated tobacco treatment into cancer care. This quality improvement (QI) project reports on the process from initial pilot to adoption within 14 ...
Fielding-Singh, Priya, Gali, Kathleen, Jimenez, Kayla, Kendra, Matthew S, Mirkin, Rachelle, Pike, Brittany, Prochaska, Judith J, Tran, Cindy   +7 more
core   +2 more sources

Economic evaluation of smoking cessation in Ontario's regional cancer programs. [PDF]

, 2018
Quitting smoking after a diagnosis of cancer results in greater response to treatment and decreased risk of disease recurrence and second primary cancers.
Cameron, Erin, Chan, Kelvin, Djalalov, Sandjar, Evans, William, Hoch, Jeffrey S, Isaranuwatchai, Wanrudee, Masucci, Lisa, Mittmann, Nicole, Peter, Alice, Rabeneck, Linda, Truscott, Rebecca   +10 more
core   +1 more source

Use of varenicline and nicotine replacement therapy in people with and without general practitioner-recorded dementia: retrospective cohort study of routine electronic medical records

BMJ Open, 2019
Objectives Our primary objective was to estimate smoking prevalence and prescribing rates of varenicline and nicotine replacement therapy (NRT) in people with and without general practitioner (GP)-recorded dementia.
Amy Taylor, Tim Jones, Taha Itani, Richard Martin, Gemma Taylor, Kyla Thomas, Neil Davies   +6 more
doaj   +1 more source

Changes in body weight and food choice in those attempting smoking cessation: a cluster randomised controlled trial [PDF]

, 2012
<p><b>Background:</b> Fear of weight gain is a barrier to smoking cessation and significant cause of relapse for many people. The provision of nutritional advice as part of a smoking cessation programme may assist some in smoking ...
AAWA van der Heijen, AC Parsons, Andrew Walker, AR Dyer, C Filozoff, Catherine R Hankey, F Pistelli, G Colletti, Heather M Murray, J Armstrong, J Stevens, JE Audrain, JE Cade, L Bauld, LR Purslow, MD Levine, MEJ Lean, MG Perri, Mhairi Mackenzie, Michael EJ Lean, P Hajek, Preethi R Koshy, R Ara, RC Klesges, S Chinn, S Rossner, St Stewart, Susan Boyle, Wilma S Leslie   +28 more
core   +3 more sources