Results 181 to 190 of about 5,243,013 (336)

An alternative surgical approach reduces variability following filament induction of experimental stroke in mice [PDF]

, 2017
Melissa Trotman‐Lucas, Michael E. Kelly, Justyna Janus, Robert Fern, Claire L. Gibson   +4 more
openalex   +1 more source

Analysis of Dual-Tasking Effect on Gait Variability While Interacting with Mobile Devices [PDF]

, 2022
David Carneros-Prado, Cosmin C. Dobrescu, Iván Gónzalez, Jesús Fontecha, Esperanza Johnson, Ramón Hervás   +5 more
openalex   +1 more source

Variable Stars [PDF]

Science, 1919
openaire   +2 more sources

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Interannual variability of sugars in Arctic aerosol: Biomass burning and biogenic inputs

, 2019
Matteo Feltracco, Elena Barbaro, Silvia Tedeschi, Andrea Spolaor, Clara Turetta, Marco Vecchiato, Elisa Morabito, Roberta Zangrando, Carlo Barbante, Andrea Gambaro   +9 more
openalex   +2 more sources

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Long-Term Atherogenic Dyslipidaemia Burden, Rather than Visit-to-Visit Variability, Is Associated with Carotid Intima-Media Thickness. [PDF]

Biomedicines
Yılmaz A, Çon E.
europepmc   +1 more source

Interannual Variability in Early Marine Growth, Size-Selective Mortality, and Marine Survival for Prince William Sound Pink Salmon

, 2009
Alison D. Cross, David A. Beauchamp, Jamal H. Moss, Katherine W. Myers   +3 more
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source