Results 261 to 270 of about 5,243,013 (336)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Dietary Escitalopram Reduces Movement Variability and Enhances Behavioral Predictability in <i>Drosophila melanogaster</i>. [PDF]

Biology (Basel)
Kolbjonoks V, Popovs S, Krams R, Trakimas G, Munkevics M, Krama T, Rantala MJ, Contreras-Garduño J, de Souza AR, Adams CB, Jõers P, Krams I.   +11 more
europepmc   +1 more source

VARIABILITY AND CORRELATION OF AGRONOMIC CHARACTERS OF MUNGBEAN GERMPLASM AND THEIR UTILIZATION FOR VARIETY IMPROVEMENT PROGRAM Lukman Hakim

, 2016
Lukman Hakim
openalex   +1 more source

Variables mediambientals = Environmental variables

Quaderns d'arquitectura i urbanisme, 1992
openaire   +2 more sources

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Antepartum Computerized Cardiotocography in High-Risk Pregnancies: Comparative Analysis of Fetal Heart Rate Parameters in Hypertensive Disorders of Pregnancy, Diabetes and Intrahepatic Cholestasis. [PDF]

J Clin Med
Danciu BM, Simionescu AA.
europepmc   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Quantifying variability of mitochondrial markers in m3243A > G myopathy. [PDF]

Sci Rep
Bernardino Gomes TM, Childs JB, Di Leo V, Warren C, Hudson G, Turnbull DM, Lawless C, Vincent AE.   +7 more
europepmc   +1 more source

Assessment of genetic variability and character association in okra genotypes for yield and contributing characters

, 2017
Meenakshi Kumari, Shashank Shekhar Solankey, Shirin Akhtar, Pallavi Neha   +3 more
openalex   +2 more sources

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source