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Protective vaccines for hypervariable pathogens are urgently needed. It has been proposed that amputating highly variable epitopes from vaccine antigens would induce the production of broadly protective antibodies targeting conserved epitopes. However, so far, these approaches have failed, partially because conserved epitopes are occluded in vivo and ...
openaire +3 more sources
Multichannel singular spectrum analysis (MSSA) of surface zonal wind, sea surface temperature (SST), 20° isotherm depth, and surface zonal current observations (between 1990 and 2004) identifies three coupled ocean–atmosphere modes of variability in the ...
Allen +37 more
core +1 more source
Among-site variability in the stochastic dynamics of East African coral reefs [PDF]
Coral reefs are dynamic systems whose composition is highly influenced by unpredictable biotic and abiotic factors. Understanding the spatial scale at which long-term predictions of reef composition can be made will be crucial for guiding conservation ...
Allen, Katherine A. +6 more
core +6 more sources
Effects of Sex and Gender on Adaptation to Space: Musculoskeletal Health [PDF]
There is considerable variability among individuals in musculoskeletal response to long-duration spaceflight. The specific origin of the individual variability is unknown but is almost certainly influenced by the details of other mission conditions such ...
Bemben, Debra +5 more
core +2 more sources
Background Uneven ground is a frequently encountered, yet little-studied challenge for individuals with amputation. The absence of control at the prosthetic ankle to facilitate correction for surface inconsistencies, and diminished sensory input from the
Jenny A. Kent +2 more
doaj +1 more source
Introduction: The seemingly periodic human gait exhibits stride-to-stride variations as it adapts to the changing task constraints. The optimal movement variability hypothesis (OMVH) states that healthy stride-to-stride variations exhibit “fractality”—a ...
Taylor J. Wilson +4 more
doaj +1 more source
Long-term glycemic variability and risk of adverse outcomes: a systematic review and meta-analysis [PDF]
OBJECTIVE: Glycemic variability is emerging as a measure of glycemic control, which may be a reliable predictor of complications. This systematic review and meta-analysis evaluates the association between HbA1c variability and micro- and macrovascular ...
Catherine Gorst +18 more
core +1 more source
Simulated methane emissions from Arctic ponds are highly sensitive to warming [PDF]
The Arctic is warming at an above-average rate, and small, shallow waterbodies such as ponds are vulnerable to this warming due to their low thermal inertia compared to larger lakes.
Z. Rehder +10 more
doaj +1 more source
Identification of a New HIV-1 BC Intersubtype Circulating Recombinant Form (CRF108_BC) in Spain
The extraordinary genetic variability of human immunodeficiency virus type 1 (HIV-1) group M has led to the identification of 10 subtypes, 102 circulating recombinant forms (CRFs) and numerous unique recombinant forms.
Javier E. Cañada +15 more
doaj +1 more source
Variability for Categorical Variables [PDF]
Introductory statistics textbooks rarely discuss the concept of variability for a categorical variable and thus, in this case, do not provide a measure of variability.
Gary D. Kader, Mike Perry
openaire +1 more source

