Results 51 to 60 of about 1,946,034 (299)

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

FEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke, Izadora Volpato Rossi, Marcel I. Ramirez   +2 more
wiley   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

On the interpretation of variables [PDF]

SIMULATION, 1985
Correct usage is discussed for concepts and terminology in various types of models, namely simulation, regression, and user's mental models. Therefore, a strict distinction is made between variables and parameters; also, different measurement scales are distinguished.
openaire   +4 more sources

Evolutionary interplay between viruses and R‐loops

FEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi, Zita Képes, Zoltán Szabó, Eszter Csoma, Lóránt Székvölgyi   +4 more
wiley   +1 more source

Design and Evaluation of a Bilateral Semi-Rigid Exoskeleton to Assist Hip Motion

Biomimetics
This study focused on designing and evaluating a bilateral semi-rigid hip exoskeleton. The exoskeleton assisted the hip joint, capitalizing on its proximity to the body’s center of mass.
Arash Mohammadzadeh Gonabadi, Prokopios Antonellis, Alex C. Dzewaltowski, Sara A. Myers, Iraklis I. Pipinos, Philippe Malcolm   +5 more
doaj   +1 more source

Assessing the Temporal Organization of Walking Variability: A Systematic Review and Consensus Guidelines on Detrended Fluctuation Analysis

Frontiers in Physiology, 2020
Human physiological signals are inherently rhythmic and have a hallmark feature in that even distant intrasignal measurements are related to each other.
Deepak K. Ravi, Vivien Marmelat, William R. Taylor, Karl M. Newell, Nick Stergiou, Navrag B. Singh   +5 more
doaj   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

NONAN GaitPrint: An IMU gait database of healthy older adults

Scientific Data
The continued effort to study gait kinematics and the increased interest in identifying individuals based on their gait patterns could be strengthened by the inclusion of data from older groups.
Tyler M. Wiles, Seung Kyeom Kim, Madhur Mangalam, Joel H. Sommerfeld, Kolby J. Brink, Alli Grunkemeyer, Marilena Kalaitzi Manifrenti, Anaelle E. Charles, Narges Shakerian, Mehrnoush Haghighatnejad, Spyridon Mastorakis, Nick Stergiou, Aaron D. Likens   +12 more
doaj   +1 more source

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

FEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao, Qiangbing Yang, Christian J.B. Snijders Blok, Mark A. Daniels, Pieter A. Doevendans, Raymond Schiffelers, Joost P.G. Sluijter, Zhiyong Lei   +7 more
wiley   +1 more source

Geometric principles of wobble board design for balance training and rehabilitation

Scientific Reports
Wobble boards—unstable platforms mounted on curved bases—are widely used for balance training and rehabilitation. However, their design lacks a systematic theoretical foundation, making it difficult to precisely tailor instability characteristics to ...
Theodore Deligiannis, Madhur Mangalam
doaj   +1 more source