Results 131 to 140 of about 557,766 (311)

Massively-Parallel Feature Selection for Big Data

, 2017
We present the Parallel, Forward-Backward with Pruning (PFBP) algorithm for feature selection (FS) in Big Data settings (high dimensionality and/or sample size).
Borboudakis, Giorgos, Christophides, Vassilis, Katsogridakis, Pavlos, Pratikakis, Polyvios, Tsamardinos, Ioannis   +4 more
core  

Bayesian clustering of multivariate extremes

Canadian Journal of Statistics, EarlyView.
Abstract The asymptotic dependence structure between multivariate extreme values is fully characterized by their projections on the unit simplex. Under mild conditions, the only constraint on the resulting distributions is that their marginal means must be equal, which results in a nonparametric model that can be difficult to use in applications ...
Sonia Alouini, Anthony C. Davison
wiley   +1 more source

When Dihedral Angles Mask Denticity in Molecular Conductance

ChemPhysChem, EarlyView.
This study tests whether higher molecule–electrode denticity increases conductance in single‐molecule junctions. Using nonequilibrium Green's function technique in conjunction with density functional theory simulations and mechanically controlled break‐junction experiments on a tetradentate N‐heterohexacene, it is found that conductance depends mainly ...
Kevin Batzinger, Dylan Dyer, M. D. Hashan C. Peiris, Tarek H. El‐Assaad, Rashmi Yohani Amarakoon Arachchige, Sam LaMotte, Dominic V. McGrath, Oliver L.A. Monti, Manuel Smeu   +8 more
wiley   +1 more source

A Semiparametric Bayesian Approach to Heterogeneous Spatial Autoregressive Models

Entropy
Many semiparametric spatial autoregressive (SSAR) models have been used to analyze spatial data in a variety of applications; however, it is a common phenomenon that heteroscedasticity often occurs in spatial data analysis.
Ting Liu, Dengke Xu, Shiqi Ke
doaj   +1 more source

Population Pharmacokinetics and Exposure–Response Analyses of Momelotinib, Its Active Metabolite (M21), and Total Active Moiety in Myelofibrosis

Clinical Pharmacology &Therapeutics, EarlyView.
Momelotinib, a Janus kinase (JAK) 1/JAK2/activin A receptor type 1 inhibitor, is approved for the treatment of myelofibrosis with anemia. These analyses characterized the population pharmacokinetics of momelotinib and its active metabolite M21 following administration of the commercial tablet formulation in patients with myelofibrosis from phase II/III
Benjamin Rich, Meenakshi Srinivasan, Yu Liu Ho, Sandra A.G. Visser, Geraldine Ferron‐Brady, Georgios Vlasakakis   +5 more
wiley   +1 more source

Straight to Phase III: Model‐Informed Approach Speeds Depemokimab Clinical Development in Interleukin‐5‐Driven Diseases

Clinical Pharmacology &Therapeutics, EarlyView.
Straight to Phase III: Model‐informed approach speeds depemokimab clinical development in interleukin‐5‐driven diseases. IL‐5, a key mediator of type 2 inflammation, underlies various diseases, including severe asthma, CRSwNP, EGPA, and HES. Reduction in blood eosinophil count (BEC), a biomarker of IL‐5 activity, is commonly used to evaluate the ...
Chiara Zecchin, Stein Schalkwijk, Isabelle J. Pouliquen, Alienor Berges, Nicholas Bird, Richard Follows, Daren Austin   +6 more
wiley   +1 more source

Reversible jump Markov chain Monte Carlo

, 2010
To appear to MCMC handbook, S. P. Brooks, A. Gelman, G. Jones and X.-L.
Fan, Y, Sisson, S A
core  

TimeFlow 2: An Unsupervised Cell Lineage Detection Method for Flow Cytometry Data

Cytometry Part A, EarlyView.
TimeFlow 2 is a new method for cell lineage inference in flow cytometry data. It constructs cell state paths along pseudotime and aggregates them into biologically informative groups. It allows tracking of cytometry markers within each automatically inferred lineage.
Margarita Liarou, Thomas Matthes, Stéphane Marchand‐Maillet   +2 more
wiley   +1 more source

Patterns of understorey bird diversity across Amazonian forests: survey effort and range maps predict local species richness

Ecography, EarlyView.
Species diversity typically increases from higher to lower latitudes, but the regional‐scale variation along this geographic gradient remains unclear. It has been suggested that species diversity throughout Amazonia generally increases westward toward the Andes, but this pattern and its environmental determinants require further investigation for most ...
Pilar L. Maia‐ Braga, Anderson S. Bueno, Marina F. A. Maximiano, Torbjørn Haugaasen, Marina Anciães, John G. Blake, Bette A. Loiselle, Sergio H. Borges, Juliana Menger, Sidnei Dantas, Ramiro D. Melinski, Affonso H. N. Souza, Fernando H. T. de Abreu, Roberta L. Boss, Carlos A. Peres   +14 more
wiley   +1 more source

Twenty years of dynamic occupancy models: a review of applications and look to the future

Ecography, EarlyView.
Since their introduction over 20 years ago, dynamic occupancy models (DOMs) have become a powerful and flexible framework for estimating species occupancy across space and time while accounting for imperfect detection. As their popularity has increased and extensions have further expanded their capabilities, DOMs have been applied to increasingly ...
Saoirse Kelleher, Gurutzeta Guillera-Arroita, Jane Elith, Natalie J. Briscoe   +3 more
wiley   +1 more source