Advanced Healthcare Materials, EarlyView.To dissect how mechanical forces influence intestinal physiology, we developed a stretchable 3D colon‐on‐chip that integrates tunable topography, stiffness and peristalsis‐like motion within a physiologically relevant microenvironment. We showed that stretching is a dominant factor governing epithelial behavior, markedly enhancing proliferation and ...
Moencopi Bernheim‐Dennery +10 more
wiley +1 more source
Neuromuscular and Kinetic Adaptations to Symmetric and Asymmetric Load Carriage During Walking in Individuals with Chronic Low Back Pain. [PDF]
Bioengineering (Basel)Tajik R +7 more
europepmc +1 more source
Flexible Polypyrrole‐Based pH Sensors via Oxidative Chemical Vapor Deposition
Advanced Healthcare Materials, EarlyView.Oxidative chemical vapor deposition (oCVD) of polypyrrole (PPy) thin films yields flexible, electrically conductive, and biocompatible pH sensors for monitoring on‐skin biological events. The highly sensitive, oCVD PPy skin‐conformal sensors enable real‐time, spatially resolved sensing of dynamic pH changes within physiologically relevant ranges (4–9 ...
Adrivit Mukherjee +15 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.xx xx. ABSTRACT Stimuli‐responsive nanomaterials capable of spatiotemporal control over drug release are of nanocomposite patch (“e‐Medi‐Patch”) engineered from biodegradable polycaprolactone (PCL), graphene nanoplatelets, and a redox‐active therapeutic, niclosamide. The hierarchical composite integrates π‐π interactions between aromatic drug molecules
Santosh K. Misra +7 more
wiley +1 more source
A Machine Learning Framework for the Reconstruction of Composite Fatigue and Fracture Properties: A Synthetic Data Study. [PDF]
Materials (Basel)Tiwari S, Gupta A.
europepmc +1 more source
Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration
Advanced Healthcare Materials, EarlyView.Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu +4 more
wiley +1 more source
Tidal and hydrological seismicity modulations reveal pore fluid diffusion during earthquake nucleation. [PDF]
Sci AdvZhao Z +5 more
europepmc +1 more source
Advanced Healthcare Materials, EarlyView.Platform system to create biofabricated 3D spinal cord tissue models: Combining high resolution PCL fiber placement, a customized, hyaluronic acid‐based hydrogel, two cell types (spinal cord neurons and astrocytes) together with three distinct laminin isoforms allow the formation of functional cell–cell network interactions.
Nicoletta Murenu +12 more
wiley +1 more source
Compilation of Load Spectrum of Loader Working Device and Application in Fatigue Life Prediction. [PDF]
Sensors (Basel)Shi X, Guo W, Wang J, Li G, Lu H.
europepmc +1 more source
Controllable Dynamic Mechanical Cell Stimulation using Magnetically Actuated Artificial Cilia
Advanced Healthcare Materials, EarlyView.This paper introduces a platform based on magnetic artificial cilia for providing controllable dynamic mechanical stimulation to single cells, suitable for investigating large cell populations and enabling live cell imaging. Proof‐of‐principle experiments show that cell morphology is strongly influenced by the artificial cilia, that cellular forces can
Roel Kooi +5 more
wiley +1 more source