Results 41 to 50 of about 27,183 (304)

Ground state solution for a class of supercritical nonlocal equations with variable exponent

Electronic Journal of Qualitative Theory of Differential Equations, 2021
In this paper, we obtain the existence of positive critical point with least energy for a class of functionals involving nonlocal and supercritical variable exponent nonlinearities by applying the variational method and approximation techniques. We apply
Xiaojing Feng
doaj   +1 more source

Fractional integrals and hypersingular integrals in variable order Hölder spaces on homogeneous spaces

Journal of Function Spaces and Applications, 2010
We consider non-standard Hölder spaces Hλ(⋅)(X) of functions f on a metric measure space (X, d, μ), whose Hölder exponent λ(x) is variable, depending on x ∈ X.
Natasha Samko, Stefan Samko, Boris Vakulov   +2 more
doaj   +1 more source

Characterizing Parental Concerns About Lasting Impacts of Treatment in Children With B‐Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background B‐acute lymphoblastic leukemia (B‐ALL) is the most common pediatric cancer, and while most children in high‐resource settings are cured, therapy carries risks for long‐term toxicities. Understanding parents’ concerns about these late effects is essential to guide anticipatory support and inform evolving therapeutic approaches ...
Kellee N. Parker, Sarah W. Alexander, Lisa M. Jacola, Kimberly A. Buff, Kyobin Hwang, Elham Hashemi, Gregory Stoddard, Lindsay A. Jibb   +7 more
wiley   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

FEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue, Sandrine Picaud, Régine Hepp, Stéphanie Pons, Uwe Maskos, Bertrand Lambolez, Ludovic Tricoire   +6 more
wiley   +1 more source

On nonlinear evolution variational inequalities involving variable exponent

Electronic Journal of Qualitative Theory of Differential Equations, 2013
In this paper, we discuss a class of quasilinear evolution variational inequalities with variable exponent growth conditions in a generalized Sobolev space. We obtain the existence of weak solutions by means of penalty method.
Mingqi Xiang
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Weighted Hardy-Type Inequalities in Variable Exponent Morrey-Type Spaces

Journal of Function Spaces and Applications, 2013
We study the p·→q· boundedness of weighted multidimensional Hardy-type operators Hwα· and ℋwα· of variable order αx, with radial weight wx, from a variable exponent locally generalized Morrey space ℒp·,φ·ℝn,w to another ℒq·,ψ·ℝn,w.
Dag Lukkassen, Lars-Erik Persson, Stefan Samko, Peter Wall   +3 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Nonlocal hyperbolic Stokes system with variable exponent of nonlinearity

Математичні Студії, 2023
In this paper, we study the problem for a nonlinear hyperbolic Stokes system of the second order with an integral term. Sufficient conditions for the uniqueness of the weak solution of this problem are found in a bounded domain. The nonlinear term of the
O. M. Buhrii, O. T. Kholyavka, T. M. Bokalo   +2 more
doaj   +1 more source