Results 61 to 70 of about 27,183 (304)
Variable Exponent Function Spaces related to a Sublinear Expectation
Abstract and Applied Analysis, 2020 In this paper, variable exponent function spaces Lp·, Lbp·, and Lcp· are introduced in the framework of sublinear expectation, and some basic and important properties of these spaces are given.
Bochi Xu
doaj +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Hölder Quasicontinuity in Variable Exponent Sobolev Spaces
Journal of Inequalities and Applications, 2007 We show that a function in the variable exponent Sobolev spaces coincides with a Hölder continuous Sobolev function outside a small exceptional set.
Kinnunen Juha +2 more
doaj
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Malliavin Derivatives in Spaces with Variable Exponents [PDF]
Journal of Function Spaces, 2014 Spaces with variable exponentsLpx(H,μ)andLpx(H,μ;H)are introduced. After discussing some approximation results ofLpx(H,μ), Sobolev spaces onHwith variable exponents are introduced. At last, we define Malliavin derivatives inLpx(H,μ)and discuss some properties of Malliavin derivatives inLpx(H,μ).
Bochi Xu, Yongqiang Fu, Boping Tian
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Multiplicity of solutions for an anisotropic variable exponent problem
Boundary Value Problems, 2022 In this manuscript an existence result for an anisotropic variable problem which is related to several applications is proved. By considering suitable hypotheses, the multiplicity of solutions is obtained.
Leandro S. Tavares
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LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Anisotropic Hardy-Lorentz Spaces with Variable Exponents [PDF]
Canadian Journal of Mathematics, 2017 AbstractIn this paper we introduceHardy-Lorentz spaces with variable exponents associated with dilations in ℝn. We establishmaximal characterizations and atomic decompositions for our variable exponent anisotropic Hardy-Lorentz spaces.
Almeida, V. +2 more
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