Results 101 to 110 of about 3,737,276 (277)

Evolutionary shift detection with ensemble variable selection

BMC Ecology and Evolution
Abrupt environmental changes can lead to evolutionary shifts in trait evolution. Identifying these shifts is an important step in understanding the evolutionary history of phenotypes. The detection performances of different methods are influenced by many
Wensha Zhang, Toby Kenney, Lam Si Tung Ho   +2 more
doaj   +1 more source

Assessment of Sentinel-2 MSI Spectral Band Reflectances for Estimating Fractional Vegetation Cover

Remote Sensing, 2018
Fractional vegetation cover (FVC) is an essential parameter for characterizing the land surface vegetation conditions and plays an important role in earth surface process simulations and global change studies.
Bing Wang, Kun Jia, Shunlin Liang, Xianhong Xie, Xiangqin Wei, Xiang Zhao, Yunjun Yao, Xiaotong Zhang   +7 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Developing an Optimal Spatial Predictive Model for Seabed Sand Content Using Machine Learning, Geostatistics, and Their Hybrid Methods

Geosciences, 2019
Seabed sediment predictions at regional and national scales in Australia are mainly based on bathymetry-related variables due to the lack of backscatter-derived data. In this study, we applied random forests (RFs), hybrid methods of RF and geostatistics,
Jin Li, Justy Siwabessy, Zhi Huang, Scott Nichol   +3 more
doaj   +1 more source

Crop classification using spectral indices derived from Sentinel-2A imagery

Journal of Information and Telecommunication, 2020
Optical remote sensing is one of the most attractive options for generating crop cover maps because it enables computation of vegetation indices, which are useful for assessing the condition of vegetation.
Nobuyuki Kobayashi, Hiroshi Tani, Xiufeng Wang, Rei Sonobe   +3 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Instrumental Variable Method for Regularized Estimation in Generalized Linear Measurement Error Models

Econometrics
Regularized regression methods have attracted much attention in the literature, mainly due to its application in high-dimensional variable selection problems.
Lin Xue, Liqun Wang
doaj   +1 more source

Fuzzy Forests: Extending Random Forest Feature Selection for Correlated, High-Dimensional Data

Journal of Statistical Software, 2019
In this paper we introduce fuzzy forests, a novel machine learning algorithm for ranking the importance of features in high-dimensional classification and regression problems. Fuzzy forests is specifically designed to provide relatively unbiased rankings
Daniel Conn, Tuck Ngun, Gang Li, Christina M. Ramirez   +3 more
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Covariate Selection for RNA-Seq Differential Expression Analysis with Hidden Factor Adjustment

Mathematics
In RNA-seq data analysis, a primary objective is the identification of differentially expressed genes, which are genes that exhibit varying expression levels across different conditions of interest.
Farzana Noorzahan, Hyeongseon Jeon, Yet Nguyen   +2 more
doaj   +1 more source