Results 261 to 270 of about 3,727,733 (308)
Multivariate Bayesian variable selection for multi-trait genetic fine mapping. [PDF]
J R Stat Soc Ser C Appl StatCanida T, Ke H, Chen S, Ye Z, Ma T.
europepmc +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Prediction of the spatial distribution of vine weevil under climate change using multiple variable selection methods. [PDF]
Sci RepKim GY, Lee WH.
europepmc +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Robust variable selection methods with Cox model-a selective practical benchmark study. [PDF]
Brief BioinformZhang Y, Muller S.
europepmc +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Variable selection strategies for genomic prediction of growth and carcass related traits in experimental Nellore cattle herds under different selection criteria. [PDF]
Sci RepMota LFM +7 more
europepmc +1 more source