Results 121 to 130 of about 657,267 (315)
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Application of traction drives as servo mechanisms [PDF]
The suitability of traction drives for a wide class of aerospace control mechanisms is examined. Potential applications include antenna or solar array drive positioners, robotic joints, control moment gyro (CMG) actuators and propeller pitch change ...
Loewenthal, S. H. +2 more
core +1 more source
Development of Single Phase Induction Motor Adjustable Speed Control Using M68HC11E9 Micro controller [PDF]
, 2004 Variable speed control of a single-phase induction motor could be obtained through voltage control method using semiconductor power devices. These methods suffer from the large harmonics that result from the switching operation.
Hussien, Hamad Saad
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Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Tuning of modern speed drives using IFOC: A case study for a five-phase induction machine
Results in EngineeringElectric machines have existed since the beginning of the 19th century. Although variable-speed drive technology has evolved considerably during the last years, the indirect field-oriented control technique has been in use as a standard control method ...
F. Barrero +3 more
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Axial force and efficiency tests of fixed center variable speed belt drive [PDF]
An investigation of how the axial force varies with the centerline force at different speed ratios, speeds, and loads, and how the drive's transmission efficiency is affected by these related forces is described.
Bents, D. J.
core +1 more source
Study of the dynamics and energy characteristics of fan installations with variable speed drive [PDF]
, 2015 В роботі розглянуті режими роботи вентиляційної установки як єдиного технологічного комплексу у складі вентилятора і асинхронного електроприводу з частотним регулюванням.
Майданский, И. Я. +2 more
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