Results 111 to 120 of about 336,215 (315)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Variable speed pumped storage hydropower for integration of wind energy in isolated grids : case description and control strategies [PDF]

, 2008
This paper presents the use of variable speed pumped storage hydropower plants for balancing power fluctuations from wind power in an isolated grid.
Suul, Jon Are, Uhlen, Kjetil, Undeland, Tore   +2 more
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Electric shock hazard in circuits with variable-speed drives [PDF]

Bulletin of the Polish Academy of Sciences: Technical Sciences, 2018
S. Czapp, J. Guzinski
doaj   +1 more source

The influence of control parameters on energy efficiency of switched reluctance generator for vehicle applications

E3S Web of Conferences, 2017
In the paper, the possibilities of application of switched reluctance generators in modern variable-speed drives were discussed. The process of mechanical energy conversion into electric energy was discussed.
Korkosz Mariusz, Powrózek Adam
doaj   +1 more source

An Investigation of the Electrical Response of A Variable Speed Motor Drive for Mechanical Fault Diagnosis [PDF]

, 2011
Motor current signal analysis has been an effective way for many years to monitor electrical machines. However, little research work has been reported in using this technique for monitoring variable speed drives and their downstream equipment. This paper
Ball, Andrew, Gu, Fengshou, Haram, Mansaf, Wang, Tie   +3 more
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Effect of Weighting Factors in Energy Efficiency of Predictive Control of Multi-Phase Drives

Applied Sciences
Predictive current control of variable speed drives by direct command of inverter states allows fast control. Its application to multiphase system constitutes a flexible solution that tackles several objectives by means of a cost function with several ...
Esteban Marsal, Manuel R. Arahal, Manuel G. Satué, Kumars Rouzbehi   +3 more
doaj   +1 more source

Variable speed drive with hydraulic boost

International Journal of Fluid Power, 2019
This paper studies a variable speed drive with two hydraulic pump motors connected to an actuator. The torque load of the pump motors is reduced by connecting different pressures to the inlets of the pump motors. A method for real-time selection of the inlet pressures is developed.
openaire   +3 more sources