Results 141 to 150 of about 108,437 (296)
Molecular Oncology, EarlyView.MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin +14 more
wiley +1 more source
Molecular Oncology, EarlyView.The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita +1 more
wiley +1 more source
The variable star S Lyncis. Two new double stars. Anderson's variable near BD. +55.°3011 [PDF]
, 1899 E. E. Barnard
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Molecular Oncology, EarlyView.NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi +5 more
wiley +1 more source
Infrared Survey of Giant M Stars
Journal of Mathematical and Fundamental Sciences, 2019 . A spectrocospic survey in an area of 5 squares degrees, located in the general direction of the Palomar-Groningen Variable-Star Field 2 , yields 263 Giant M stars.
Bambang Hidajat
doaj
On a new and remarkable variable star in the constellation Ara
, 1877 John Tebbutt
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