Results 201 to 210 of about 5,204,122 (311)
Detection of Expressed <i>Otx</i> mRNA Isoforms in Sea Urchins by Mapping NGS Reads to Single-Gene/Transcript Sequences. [PDF]
Maiorova MA +2 more
europepmc +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Unveiling the formation mechanism of workplace deviance among front-line star nurses. [PDF]
Liu Z, Dong Y.
europepmc +1 more source
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Robust Beamforming Design for Energy Efficiency and Spectral Efficiency Tradeoff in Multi-STAR-RIS-Aided C-HRSMA. [PDF]
Teng S, Lin X, Wang Y.
europepmc +1 more source
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Optimizing the angle of arrival positioning error of a UAV via an improved nutcracker optimization algorithm. [PDF]
Li Y, Hu Q, Sun S, Ying W, Yan X.
europepmc +1 more source
The variable star S Lyncis. Two new double stars. Anderson's variable near BD. +55.°3011
E. E. Barnard
openalex +2 more sources
Massive star evolution: luminous blue variables as unexpected supernova progenitors [PDF]
J. H. Groh, G. Meynet, S. Ekström
openalex +1 more source

