Results 171 to 180 of about 51,534 (310)
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Unwrapping the mirror tracing task. [PDF]
Garrido PF +6 more
europepmc +1 more source
Searching for new variable stars
A method of finding new variable stars is presented in this work. The method is based on observations from ground-based telescopes processed using the SIPS and SILICUPS pro- grams, with data from the TESS satellite used to confirm the variability.
Odorčák, Marek
core
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Exploring the role of admiration in mitigating athlete burnout: an emotional perspective. [PDF]
Xu W, Tian S, Song T, Chen S, Pan Y.
europepmc +1 more source
High School Students Watching Stars Evolve
We describe a study of period changes in 59 RR Lyrae stars, using times of maximum brightness from the GEOS database. The work was carried out by outstanding senior high school students in the University of Toronto Mentorship Program.
MacNeil, Drew +3 more
core
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source

