Results 121 to 130 of about 8,444,075 (296)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Advanced incremental conductance MPPT algorithm with a variable step size

open access: yes, 2006
—This paper proposes an advanced Incremental Conductance MPPT algorithm with a variable step size for a solar array regulator (SAR) system. This approach adjusts automatically a step size to the solar array operating point, thus improving the MPPT ...
Hyunsu Bae   +4 more
core   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

GWO and WOA variable step MPPT algorithms-based PV system output power optimization

open access: yesScientific Reports
The nonlinear characteristics and low efficiency of photovoltaic (PV) systems remain critical challenges that necessitate advanced solutions. This study proposes two innovative Maximum Power Point Tracking (MPPT) algorithms based on the Whale ...
Abderrahim Zemmit   +6 more
doaj   +1 more source

A Variable Step-Size Diffusion LMS Algorithm for Distributed Estimation

open access: yes, 2018
We propose a new variable step-size diffusion least mean square algorithm for distributed estimation that adaptively adjusts the step-size in every iteration.
Kim, SE, Song, WJ, Lee, JW, Lee, HS
core   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Hardware Efficient Adaptive Beamformer Based on Cyclic Variable Step Size

open access: yes, 2019
This paper presents an improved adaptive beamforming solution based on Global Sidelobe Canceler (GSC) and Least Mean Square (LMS). By analyzing the impact of step size on LMS performance, a simple yet effective new Cyclic Variable Step Size (CVSS ...
Dai, Shaowei   +3 more
core   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The Wavelet Transform-Domain LMS Adaptive Filter Algorithm with Variable Step-Size

open access: yesIranian Journal of Electrical and Electronic Engineering, 2017
The wavelet transform-domain least-mean square (WTDLMS) algorithm uses the self-orthogonalizing technique to improve the convergence performance of LMS.
M. Shams Esfand Abadi   +2 more
doaj  

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