Results 81 to 90 of about 2,983,370 (285)

Variable Step-Size Control Based on Two-Steps for Radau IIA Methods

open access: yesACM Transactions on Mathematical Software, 2020
Two-step embedded methods of order s based on s -stage Radau IIA formulas are considered for the variable step-size integration of stiff differential equations. These embedded methods are aimed at local error control and are computed through a linear combination of the internal stages of the ...
Severiano González Pinto   +2 more
openaire   +2 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

A variable step size fuzzy MPPT controller improving energy conversion of variable speed DFIG wind turbine

open access: yesRevue des Énergies Renouvelables, 2017
With the world’s fastest growing rate and the prominent part of installed renewable energy sources, it is clear that wind is now a mainstream source of energy supply that will play a leading role in the proclaimed fight against climate change.
A. Harrag, S. Messalti
doaj  

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

A Transient Stability Numerical Integration Algorithm for Variable Step Sizes Based on Virtual Input

open access: yesEnergies, 2017
In order to reduce the online calculations for power system simulations of transient stability, and dramatically improve numerical integration efficiency, a transient stability numerical integration algorithm for variable step sizes based on virtual ...
Yifan Gao   +3 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Steady state oscillations reduction using neural network IC-based variable step Size MPPT

open access: yesRevue des Énergies Renouvelables, 2016
This paper deals with the development of neural network IC-based variable step size MPPT controller. The proposed neural network MPPT controller is firstly, developed in offline mode required for testing different set of neural network parameters and ...
A. Harrag, H. Bahri, S. Messalti
doaj  

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

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