Results 51 to 60 of about 2,092,411 (198)

Diffusion‐Based Generative Model With Scaffold‐Hopping Strategy Yields Highly Potent Bioactive Molecules

Advanced Science, Volume 13, Issue 44, 7 August 2026.
SMarT‐Diff introduces a multi‐objective generative paradigm that integrates scaffold hopping with structure‐aware scoring to enable controlled exploration beyond the training distribution. The framework consistently balances drug‐likeness, synthesizes accessibility and bioactivity, yielding chemically diverse candidates with enhanced properties.
Yuwei Yang, Xiaoqing Gong, Shukai Gu, Jing Li, Bo Liu, Yanan Tian, Qianqian Zhang, Xiaojun Yao, Huanxiang Liu   +8 more
wiley   +1 more source

A Novel Optimized Local Linearization Hybrid Block Method for Chaotic Systems: Applications to Stretch‐Twist‐Fold Flow and Bond Orbital Chaotic Attractors

Mathematical Methods in the Applied Sciences, Volume 49, Issue 12, Page 13148-13175, August 2026.
ABSTRACT The numerical approximation of nonlinear chaotic differential systems, such as the modified stretch‐twist‐fold (STF) flow and multi‐bond chaotic attractors, presents a significant challenge due to their sensitive dependence on initial conditions and complex dynamics where analytical solutions are unattainable.
Shina Daniel Oloniiju, Anastacia Dlamini
wiley   +1 more source

Accurate Sizing and Resolution of Nominal 200 nm Diameter Polystyrene Nanospheres With Charge Detection Mass Spectrometry

Small, Volume 22, Issue 43, 3 August 2026.
This study highlights the utility of charge detection mass spectrometry (CDMS) as a high‐throughput nanoparticle characterization tool. CDMS measurements of 200 nm polystyrene size standards are within 1% of those derived from transmission electron microscopy (TEM). Notably, a mixture of three ∼200 nm samples is readily resolved by CDMS but not by TEM,
Veena S. Avadhani, Conner C. Harper, Evan R. Williams   +2 more
wiley   +1 more source

Improved variable step-size LMS algorithm based on hyperbolic tangent function

Tongxin xuebao, 2020
In order to improve that the LMS algorithm for determining step size cannot satisfy both rapid convergence and low steady-state misalignment errors,a variable step size algorithm (IVSSLMS) based on an improved hyperbolic tangent function was proposed.The
Jianwu ZHANG, Hao YU, Qianhua ZHANG
doaj   +2 more sources

Dislocation Bands and Subboundaries in Experimentally Deformed Olivine

Journal of Geophysical Research: Solid Earth, Volume 131, Issue 8, August 2026.
Abstract Transmission electron microscopy imaging of dislocations in olivine indicates heterogeneous structures and diversity of dislocation types. However, the volumes imaged at high resolution are smaller than individual grains even of fine‐grained samples.
Ulrich Faul
wiley   +1 more source

Convergent Interval Confirmation for Three‐Step Discrete Specific Zeroing Neural Dynamics Illustrated With Repetitive Motion Planning of Redundant Manipulators

CAAI Transactions on Intelligence Technology, Volume 11, Issue 4, Page 1274-1283, August 2026.
ABSTRACT Repetitive motion planning (RMP) for redundant manipulators with high convergent precision becomes an intense research topic due to its more degrees of freedom. In this paper, a specific zeroing neural dynamics (SZND) model for the RMP is first set up via zeroing neurodynamics.
Ying Kong, Shaoyuan Sun, Yunliang Jiang, Lin Wei   +3 more
wiley   +1 more source

A kind of adaptive variable stepsize embedded Runge–Kutta pairs coupled with the Sinc collocation method for solving the KdV equation

Results in Applied Mathematics
For solving the KdV equation, a novel numerical method with high order accuracy in both space and time is proposed. In the spatial direction, Sinc collocation method, which has the property of exponential convergence, is adopted.
Cheng Chen, Wenting Shao
doaj   +1 more source

Improving the Numerical Solution of the Energy Equation in Land Models

Journal of Advances in Modeling Earth Systems, Volume 18, Issue 7, July 2026.
Abstract The purpose of this study is to improve simulations of the energy equation in land models. Our objectives are to (a) highlight the shortcomings of current approaches for solving the energy equation in land models; (b) present improved solutions; and (c) evaluate tradeoffs between numerical errors and strict energy conservation in the energy ...
Ashley E. Van Beusekom, Raymond J. Spiteri, Martyn P. Clark   +2 more
wiley   +1 more source

Optimizing 3D Bin Packing of Heterogeneous Objects Using Continuous Transformations in SE(3)

Advanced Intelligent Systems, Volume 8, Issue 6, June 2026.
This article presents a method for solving the three‐dimensional bin packing problem for heterogeneous objects using continuous rigid‐body transformations in SE(3). A heuristic optimization framework combines signed‐distance functions, neural network approximations, point‐cloud bin modeling, and physics simulation to ensure feasibility and stability ...
Michele Angelini, Marco Carricato
wiley   +1 more source

A new variable step-size adaptive based on Sigmoid function

Dianzi Jishu Yingyong
Aiming at the contradiction between the convergence speed and the steady state error of the fixed step size least mean square(LMS) algorithm, a novel variable step-size algorithm is proposed. The algorithm is based on the Sigmoid function and establishes
Wu Yifan, Ma Lingkun, Yan Meiyi
doaj   +1 more source