Results 111 to 120 of about 3,845,026 (318)
ASSESSMENT OF KNOWLEDGE REGARDING HYPERTENSION AMONG UNIVERSITY STUDENTS
Background: Hypertension is a major health problem in Pakistan. The objective of the study was to determine the distribution of knowledge regarding hypertension among the university students. Material & Methods: This cross sectional study was conducted
Sheikh Abdur Rashid +5 more
doaj
Structural Matrix Analysis of Variable Curvature Curved Beam [PDF]
Changjun Dong
openalex +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Learning in Integer Latent Variable Models with Nested Automatic Differentiation [PDF]
Daniel Sheldon +2 more
openalex +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
En la práctica son frecuentes los procesos industriales, en particular en la industria azucarera, donde están establecidos límites de especificación de las variables (tolerancia). Estos procesos están sometidos naturalmente a la dispersión de los valores
Erenia Cabrera Delgado +2 more
doaj
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Implication of a P-L Relation of Mira Variables [PDF]
Hiromoto Shibahashi
openalex +1 more source

