Results 241 to 250 of about 12,765,594 (335)

Vm–MSI: a Vancomycin–Antimicrobial Peptide Conjugate Combating Resistant Bacteria and Broadening the Antimicrobial Spectrum

Advanced Science, EarlyView.
A series of vancomycin‐antimicrobial peptide conjugates is synthesized and evaluated to identify the optimal combination. Vm‐MSI, selected from multiple candidates, exhibited potent activity against vancomycin‐resistant and Gram‐negative bacteria by disrupting membranes and inducing oxidative stress, thereby expanding vancomycin's antibacterial ...
Shuangyu Li, Kang Wang, Wenzhuang Shi, Xu Wang, Duxin Li, Yanli Liu, Peng Zhang, Yipeng Wang   +7 more
wiley   +1 more source

Psychometric Properties of the Digital Well-Being Scale and Its Links to Fear of Missing Out and Digital Identity. [PDF]

Behav Sci (Basel)
Gómez Yepes T, Etchezahar E, Ungaretti J, Sánchez Pujalte ML.   +3 more
europepmc   +1 more source

Ecologically‐Valid Emotion Signatures Enhance Mood Disorder Diagnostics

Advanced Science, EarlyView.
This study identifies ecologically‐valid Divergent Emotional Functional Networks (DEFN), derived from dynamic functional connectivity during naturalistic movie watching. The DEFN reliably enhances diagnostic accuracy for mood disorders, including major depressive and bipolar disorders, demonstrating strong reproducibility across demographic factors and
Shuyue Xu, Linling Li, Ting Luo, Gan Huang, Li Zhang, Benjamin Becker, Zhen Liang   +6 more
wiley   +1 more source

Geographic and Socioeconomic Determinants of Treatment Abandonment in Pediatric Acute Leukemia: A Cohort Study in South-Central Mexico. [PDF]

Cancer Control
Núñez-Enriquez JC, Luna-Silva NC, Jacuinde-Trejo K, Flores-Lujano J, Medina-León D, Alarcón-Ruiz E, Garrido-Hernández MÁ, Cruz-Medina CS, Tinoco-Montejano D, Baños-Lara MDR, Campo-Martínez MLÁD, Duarte-Rodríguez DA, Allende-López A, Casique-Aguirre D, Elizarrarás-Rivas J, Olvera-Caraza D, Solís-Poblano JC, Terán-Cerqueda V, Ramírez-Ramírez D, Huerta-Moreno A, Aristil-Chery PM, Romo-Rodríguez R, Alvarez-Rodríguez E, Lien-Chang LEJ, Zamora-Herrera G, Hidalgo BG, Herrera-Olivares W, Ruíz-Arguelles GJ, Gallardo-Pérez MM, Chávez-Aguilar LA, Márquez-Toledo A, Cano-Cuapio LS, Ramos RH, Martínez-Martell MA, Ramirez-Ramirez AB, Brindis NR, Montiel-Jarquín AJ, Galván-Díaz CA, Velasco-Hidalgo L, Medina-Sanson A, Gutiérrez-Rivera ML, Cárdenas-Conejo A, Morales-Maravilla A, Victorio-García NP, Bekker-Méndez VC, Romero-Tlalolini MLÁ, Rodríguez-Espinosa JC, Mata-Rocha M, Olivares-Sosa AI, Rosas-Vargas H, Jiménez-Morales S, Martínez MEJ, Cárdenas-González M, Mejía-Aranguré JM, López-Aguilar E, Zapata-Tarrés M, Pelayo R.   +56 more
europepmc   +1 more source

Vitamin D Regulates Olfactory Function via Dual Transcriptional and mTOR‐Dependent Translational Control of Synaptic Proteins

Advanced Science, EarlyView.
Vitamin D (VitD) modulates olfactory function by remodeling dendrodendritic synapses in tufted cells through vitamin D receptor‐dependent transcriptional and translational mechanisms. VitD regulates synaptic protein translation partially via mTOR signaling.
Pengcheng Ren, Renhe Cao, Xiaoshan Ye, Wenbin Pang, Qingshang Bi, Meihui Huang, Qionglin Zhou, Dan Ye, Wei Xiang, Le Xiao   +9 more
wiley   +1 more source

Reliability and convergent validity of the PHQ-2 for the rapid detection of depressive symptoms in healthcare professionals in Argentina. [PDF]

Front Psychiatry
Caldichoury N, Morales-Asencio B, Coronado JC, Castellanos-Alvarenga LM, Quispe-Ayala C, Saldías C, Salazar D, Ripoll-Córdoba D, Bada W, Martínez J, Duhalde-Sanhueza R, Castellanos C, Flórez Y, Quincho-Apumayta R, Ardila-Duarte C, Patiño-Rivera AR, Gargiulo PA, Cárdenas J, López N.   +18 more
europepmc   +1 more source

Gut Microbiota‐Derived Anandamide Mediates the Therapeutic Effects of Urolithin A on Alcohol‐Induced Cognitive and Social Dysfunction via CB1R‐DRD2‐RAP1 Signaling Axis

Advanced Science, EarlyView.
This study reveals that Urolithin A (UA) counteracts alcohol‐induced cognitive and social dysfunction (AICSD) via a gut microbiome‐dependent mechanism. UA‐enriched Bacteroids sartorii and Parabacteroids distasonis elevate anandamide (AEA), which activates the CB1R‐DRD2‐Rap1 signaling cascade to drive synaptic repair and reduce neuroinflammation ...
Hongbo Zhang, Zibin Li, Yao Xiao, Ji Bian, Caian He, Chao Liu, Lan Gong, Lin Han, Zhigang Liu, Min Wang   +9 more
wiley   +1 more source

Exploring the intersection of climate change, gender, and food security in Latin America [PDF]

Biomedica
Cediel-Becerra N, Sánchez-Arévalo D.
europepmc   +1 more source

Gut Bacteria Improve Depressive Symptoms by Degrading Cortisol into Androgen

Advanced Science, EarlyView.
Chronic stress is an important risk factor for stress‐related disorders such as depression. Stress hormone cortisol is essential for the pathogenesis of stress‐related disorders such as depression. Some gut microbiota degraded cortisol, and improve depressive symptoms.
Xiong Wang, Qing Wu, Hao‐Long Zeng, Yin Shen, Hong‐Han Zhang, Jun Gong, Qi Zhang, Jia‐Zhao Xie, Da‐Wei Ye, Zi‐Yong Sun, Zhong‐Chun Liu, Li‐Ming Cheng, Di Li   +12 more
wiley   +1 more source

[Paths to mainstreaming gender and intersectionality in neglected tropical disease programsCaminhos para a inclusão da perspectiva de gênero e interseccionalidade nos programas de doenças tropicais negligenciadas]. [PDF]

Rev Panam Salud Publica
Neves-Silva P, Saleh-Ramírez A, Luciañez A.   +2 more
europepmc   +1 more source