FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Reliability, bias, and computational cost of estimating the Bayes factor using bridge sampling and the Savage-Dickey density ratio. [PDF]
Behav Res MethodsOberauer K, Musfeld P, Aust F.
europepmc +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Robust Bayesian hypothesis testing with the hierarchical EZ-DDM. [PDF]
Behav Res MethodsChávez De la Peña AF +2 more
europepmc +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Author Correction: Kriging-based surrogate data-enriching artificial neural network prediction of strength and permeability of permeable cement-stabilized base. [PDF]
Nat CommunWang X +6 more
europepmc +1 more source
Psychometric evaluation of a four-item scale derived from the PHQ-9 and GAD-7 among community adults based on multivariate generalizability theory and item response theory. [PDF]
Front PsycholCheng N +10 more
europepmc +1 more source
Myths and realities: effort and response distortion in low-stakes, self-report assessments of noncognitive skills. [PDF]
Front PsycholMarkle R, Wang Z.
europepmc +1 more source