Results 231 to 240 of about 5,329,875 (275)

Approximating evidence via bounded harmonic means. [PDF]

Stat Comput
Naderi D, Robert CP, Kamary K, Wraith D.
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Operating characteristics of agreement metrics in AI-based scoring: a Monte Carlo simulation. [PDF]

Front Psychol
Yandi A.
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Effects of Sample Deposition Medium and Drying on Spectroscopic Quantification of Lipid Biomarkers in Respiratory Distress Syndrome. [PDF]

Biosensors (Basel)
Luo ZH, Ahmed W, Postle AD, Dushianthan A, Grocott MPW, Senthil Murugan G.   +5 more
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Variation in Tree Growth Increases With Global Warming. [PDF]

Ecol Lett
Li J, He F.
europepmc   +1 more source

The effect of long-range linkage disequilibrium on allele-frequency dynamics under stabilizing selection. [PDF]

PLoS Genet
Negm S, Veller C.
europepmc   +1 more source

Correcting for unequal variance in signal detection models using response time. [PDF]

iScience
Miyoshi K, Rahnev D, Lau H.
europepmc   +1 more source

Differentiating Variance for Variance-Aware Inverse Rendering

SIGGRAPH Asia 2024 Conference Papers
Kai Yan, Vincent Pegoraro, Marc Droske, Jiří Vorba, Shuang Zhao   +4 more
openaire   +1 more source