Results 111 to 120 of about 5,872,567 (354)

Accounting for biological variance in deconvolution of tissue expression

, 2020
Tissue samples are heterogeneous mixtures of component cell-types exhibiting unique functions and expression signatures. In analyses of tissue-level gene expression data, it is uncertain whether differences between samples should be attributed to changes in cellular function or composition. Deconvolution methods allow us to control for this uncertainty
Brehm, Zachary, Halushka, Marc, McCall, Matthew   +2 more
openaire   +1 more source

Testing gravity on large scales. The skewness of the galaxy distribution at z~1

, 2008
We study the evolution of the low-order moments of the galaxy overdensity distribution over the redshift interval 0 ...
Abbas, U., Adami, C., Arnouts, S., Bardelli, S., Bolzonella, M., Bondi, M., Bongiorno, A., Bottini, D., Brinchmann, J., Brun, V. Le, Buzzi, A., Cappi, A., Charlot, S., Ciliegi, P., Contini, T., Cucciati, O., de la Torre, S., de Ravel, L., Fevre, O. Le, Foucaud, S., Franzetti, P., Garilli, B., Gavignaud, I., Gregorini, L., Guzzo, L., Ilbert, O., Iovino, A., Lamareille, F., Maccagni, D., Marano, B., Marinoni, C., Mathez, G., Mazure, A., McCracken, H. J., Mellier, Y., Meneux, B., Merighi, R., Merluzzi, P., Paltani, S., Pellò, R., Perez-Montero, E., Picat, J. P., Pollo, A., Pozzetti, L., Radovich, M., Scaramella, R., Scodeggio, M., Taxil, P., Temporin, S., Tresse, L., Vergani, D., Vettolani, G., Virey, J. M., Walcher, C. J., Zamorani, G., Zanichelli, A., Zucca, E.   +56 more
core   +1 more source

A convenient regression formula for predicting Skytrax’s Official World Airport Star ratings [PDF]

, 2011
Skytrax audits and ranks airports internationally in its yearly ‘Official World Airport Star Ranking’. Unfortunately, its activity is severely restricted, at most covering just 3% of those airports listed by Skytrax as open to review by passengers in ...
Gilbey, Andrew, Pérezgonzález, Jose D.
core  

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

PENGARUH PERUBAHAN STANDAR AKUNTANSI KEUANGAN (SAK) TERHADAP EFISIENSI BANK PERKREDITAN RAKYAT (BPR) DENGAN PENDEKATAN DATA ENVELOPMENT ANALYSIS (DEA)

El Muhasaba: Jurnal Akuntansi, 2013
The study was conducted to examine the effect of changes in Financial Accounting Standards (SAK) business Rural Bank (BPR), with the enactment of the Financial Accounting Standards Un Accountability Public-entity-(SAK-ETAP) and the Rural Bank Accounting ...
Suprihadi Suprihadi
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

SNP-based mate allocation strategies to maximize total genetic value in pigs

Genetics Selection Evolution, 2019
Background Mate allocation strategies that account for non-additive genetic effects can be used to maximize the overall genetic merit of future offspring.
David González-Diéguez, Llibertat Tusell, Céline Carillier-Jacquin, Alban Bouquet, Zulma G. Vitezica   +4 more
doaj   +1 more source

Researchers’ choice of the number and range of levels in experiments affects the resultant variance-accounted-for effect size [PDF]

, 2016
Kensuke Okada, Takahiro Hoshino
openalex   +1 more source