Results 181 to 190 of about 8,447,173 (379)

C. R. Henderson, the Statistician; And His Contributions to Variance Components Estimation

, 1991
S. R. Searle
openalex   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Estimation of additive and dominance variance components in finite polygenic models and complex pedigrees [PDF]

, 1999
F.-X. DU, Ina Hoeschele, K. M. GAGE-LAHTI   +2 more
openalex   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Restricted maximum-likelihood method for learning latent variance components in gene expression data with known and unknown confounders. [PDF]

G3 (Bethesda), 2022
Malik MA, Michoel T.
europepmc   +1 more source

On unbiased estimation in variance component models

, 1965
Rodney P. Basson
openalex   +1 more source

Estimation of variance components, genetic parameters and genetic trends for litter size of swines [PDF]

, 2010
Leandro Teixeira Barbosa, Paulo Sávio Lopes, Adair José Regazzi, Robledo de Almeida Torres, MARIA LUIZA ALVES SANTANA, Renata Veroneze   +5 more
openalex   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Use of Host Feeding Behavior and Gut Microbiome Data in Estimating Variance Components and Predicting Growth and Body Composition Traits in Swine. [PDF]

Genes (Basel), 2022
He Y, Tiezzi F, Jiang J, Howard JT, Huang Y, Gray K, Choi JW, Maltecca C.   +7 more
europepmc   +1 more source

Book Review: Components of Variance [PDF]

, 2008
Walter Freiberger
openalex   +1 more source