Results 181 to 190 of about 817,120 (303)

Influence of Uninformative Prior Distributions for MCMC Method on Estimating Variance Components in Generalizability Theory. [PDF]

Appl Psychol Meas
Li G.
europepmc   +1 more source

Use of Host Feeding Behavior and Gut Microbiome Data in Estimating Variance Components and Predicting Growth and Body Composition Traits in Swine. [PDF]

Genes (Basel), 2022
He Y, Tiezzi F, Jiang J, Howard JT, Huang Y, Gray K, Choi JW, Maltecca C.   +7 more
europepmc   +1 more source

Common Functional Principal Components [PDF]

Functional principal component analysis (FPCA) based on the Karhunen-Lo`eve decomposition has been successfully applied in many applications, mainly for one sample problems.
Michal Benko, Alois Kneip, Wolfgang Härdle   +2 more
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Biological variation of baseline serum cortisol concentration in healthy dogs, part 1: variance components. [PDF]

Front Vet Sci
Wicker S, Craig S, Albright J, Springer C, Freeman K, Giori L.   +5 more
europepmc   +1 more source

Performance, Variance Components, and Acceptability of Pro-vitamin A-Biofortified Sweetpotato in Southern Africa and Implications in Future Breeding. [PDF]

Front Plant Sci, 2021
Gasura E, Matsaure F, Setimela PS, Rugare JT, Nyakurwa CS, Andrade M.   +5 more
europepmc   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Posterior estimation of longitudinal variance components from nonlongitudinal data using Bayesian Gaussian process model. [PDF]

Genetics
Arjas A, Leppälä K, Sillanpää MJ.
europepmc   +1 more source

Predicting the purebred-crossbred genetic correlation from the genetic variance components in the parental lines. [PDF]

Genet Sel Evol, 2021
Duenk P, Bijma P, Wientjes YCJ, Calus MPL.   +3 more
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source