Results 211 to 220 of about 2,181,553 (341)

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Using Longitudinal Variance Components Models to Assess Hyper-connectivity in Severe Traumatic Brain Injury Patients. [PDF]

Basic Clin Neurosci
Olazadeh K, Borumandnia N, Habibi M, Alavi Majd H.   +3 more
europepmc   +1 more source

Analysis of Components of Variances for Yield and Its Component Traits in Bread Wheat (Triticum aestivum L. em. Thell)

R. N. Raut, Kavita Krushnaji More, N.S. Talekar   +2 more
openalex   +1 more source

A Variance-Components Model for Distance-Matrix Phylogenetic Reconstruction

, 2011
Walter R. Gilks, Tom M. W. Nye, Píetro Lió   +2 more
openalex   +2 more sources

dearseq : a variance component score test for RNA-Seq differential analysis that effectively controls the false discovery rate [PDF]

, 2019
Marine Gauthier, Denis Agniel, Rodolphe Thiébaut, Boris P. Hejblum   +3 more
openalex   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

A scalable and robust variance components method reveals insights into the architecture of gene-environment interactions underlying complex traits. [PDF]

Am J Hum Genet
Pazokitoroudi A, Liu Z, Dahl A, Zaitlen N, Rosset S, Sankararaman S.   +5 more
europepmc   +1 more source

Testing Variance Components in Linear Mixed Modeling Using Permutation. [PDF]

Multivariate Behav Res, 2020
Du H, Wang L.
europepmc   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

THI Modulation of Genetic and Non-genetic Variance Components for Carcass Traits in Hanwoo Cattle. [PDF]

Front Genet, 2020
Chung Y, Lee SH, Lee HK, Lim D, van der Werf J, Lee SH.   +5 more
europepmc   +1 more source