Results 111 to 120 of about 7,160,092 (306)

Assessing the quality of generalized variance functions

AStA Wirtschafts- und Sozialstatistisches Archiv
Abstract Generalized variance functions (GVFs) are widely used in official statistics to approximate sampling variances when direct variance estimation is impractical. However, their reliability is highly context-dependent. This study evaluates GVF performance through guided modeling strategies and simulation studies across diverse ...
Inken Siems, Ralf Thomas Münnich
openaire   +3 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Lower bounds for variances of Poisson functionals

Electronic Journal of Probability
Lower bounds for variances are often needed to derive central limit theorems. In this paper, we establish a lower bound for the variance of Poisson functionals that uses the difference operator of Malliavin calculus. Poisson functionals, i.e. random variables that depend on a Poisson process, are frequently studied in stochastic geometry.
Schulte, Matthias, Trapp, Vanessa
openaire   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Linear Canonical Transform Approach to the Characteristic Function of Real Random Variables

Eng
The present research demonstrates the utility of the linear canonical transform (LCT) in constructing the characteristic function of real random variables. We refer to this construction as the linear canonical characteristic function (LCCF). The proposed
Risnawati Ibnas, Mawardi Bahri, Nasrullah Bachtiar, Syamsuddin Toaha, Andi Tenri Ajeng Nur   +4 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

EFFECT OF SHOCKS OF AGRICULTURAL TERMS OF TRADE (TOT) ON SOME AGRICULTURAL INDICATORS IN IRAQ FOR THE PERIOD (1990 - 2019)

The Iraqi Journal of Agricultural science
This study aimed to investigate the impact of agricultural TOT shocks and the strength of their effects on some indicators of the agricultural sector. The research uses VAR, Variance decomposition and IRF approaches.
AlAttabi, H. A., B. H. AlBadri
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Variance analysis and linear contracts in agencies with distorted performance measures [PDF]

This paper investigates the role of variance analysis procedures in aligning objectives under the condition of distorted performance measurement. A riskneutral agency with linear contracts is analyzed, whereby the agent receives postcontract, pre ...
Budde, Jörg
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source