Adaptive dynamics of quantitative traits in a steadily changing environment. [PDF]
GeneticsPahujani S, Zhang Y, Stetter MG, Krug J.
europepmc +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Guidance for data analysis in split-plot designs when parametric assumptions are violated: <i>F</i>-statistic, adjusted <i>F</i>-tests, and bootstrap-<i>F</i>. [PDF]
Front PsycholBlanca MJ +5 more
europepmc +1 more source
On efficiency of mean-variance based portfolio selection in DC pension schemes [PDF]
We consider the portfolio selection problem in the accumulation phase of a defined contribution (DC) pension scheme. We solve the mean-variance portfolio selection problem using the embedding technique pioneered by Zhou and Li (2000) and show that it is ...
Elena Vigna
core
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
AN EVALUATION OF EXPECTED VALUE AND EXPECTED VALUE-VARIANCE CRITERIA IN ACHIEVING RISK EFFICIENCY IN CROP SELECTION [PDF]
This article evaluates the performance of expected value and expected value-variance criteria in achieving risk efficiency in crop selection. Results indicate that the expected returns criterion achieves risk efficiency in many situations because of ...
Reid, Donald W., Tew, Bernard V.
core
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Analyzing an organism's sensors using Maximum Entropy (MaxEnt) models with bias, variance, and confusion matrices. [PDF]
PLoS OneWang C +6 more
europepmc +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
How to Measure the Reliability of Tasks in Experimental Psychology. [PDF]
J CognBrysbaert M.
europepmc +1 more source