Results 51 to 60 of about 123,350 (264)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

ESTIMATION OF INTRUSION DETECTION PROBABILITY BY PASSIVE INFRARED DETECTORS [PDF]

open access: yesНаучно-технический вестник информационных технологий, механики и оптики, 2015
Subject of Research. The paper deals with estimation of detection probability of intruder by passive infrared detector in different conditions of velocity and direction for automated analyses of physical protection systems effectiveness. Method. Analytic
V. V. Volkhonskiy, S. L. Malyshkin
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Comparison of methods of approximating option prices with Variance gamma processes

open access: yesKorean Journal of Applied Statistics, 2016
We consider several methods to approximate option prices with correction terms to the Black-Scholes option price. These methods are able to compute option prices from various risk-neutral distributions using relatively small data and simple computation.
Jaejoong Lee, Seongjoo Song
openaire   +2 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Bayesian optimization of EWMA control charts: A case on process variance monitoring

open access: yesKuwait Journal of Science
Bayesian control charts (BCC) are gaining prominence as powerful statistical process control tools for analyzing manufacturing processes and managing process variability.
Tahir Abbas   +3 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Keeping risk alive

open access: yesRisk Sciences
Risk premia in markets rise with the degree of discontinuity in price motion. This discontinuity is measured by the scale and speed coefficients of price movements embedded in the bilateral gamma process, which is modeled as the difference of two ...
Dilip B. Madan, King Wang
doaj   +1 more source

Bayesian Approach for Confidence Intervals of Variance on the Normal Distribution

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2022
This research aims to compare estimating the confidence intervals of variance based on the normal distribution with the primary method and the Bayesian approach. The maximum likelihood is the well-known method to approximate variance, and the Chi-squared
Autcha Araveeporn
doaj   +1 more source

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