Results 51 to 60 of about 91,741 (276)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Generalised Hyperbolic State-Space Models for Inference in Dynamic Systems
IEEE Open Journal of Signal ProcessingIn this work we study linear vector stochastic differential equation (SDE) models driven by the generalised hyperbolic (GH) Lévy process for inference in continuous-time non-Gaussian filtering problems. The GH family of stochastic processes offers
Yaman Kindap, Simon Godsill
doaj +1 more source
Geosciences, 2018 A simplified geostatistical approach was adopted to assess the effect of spatial variability of soil properties on slope stability analysis in order to understand continental margin geologic processes and potential geohazards for an area of the central ...
Kevin MacKillop +4 more
doaj +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Weak Subordination of Multivariate Lévy Processes [PDF]
, 2018 Based on the idea of constructing a time-changed process, strong subordination is the operation that evaluates a multivariate Lévy process at a multivariate subordinator.
Lu, Kevin Weichao
core +1 more source
PLoS ONE, 2019 Television (TV) programming attracts ever-growing audiences and dominates the cultural zeitgeist. Viewership and social media engagement have become standard indices of programming success.
Avgusta Y Shestyuk +4 more
doaj +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
, 2019 The class of Esscher transforms is an important tool for option pricing Gerber and Shiu (1994) showed that the Esscher transform is an efficient technique for valuing derivative securities if the log returns of the underlying securities are governed by ...
Troush, N.N., Kuzmina, A.V.
core +2 more sources