Results 141 to 150 of about 1,548,550 (297)

Development and deployment of a public mid-density genotyping panel for crimson clover (Trifolium incarnatum L.) based on whole-genome re-sequencing of diverse germplasm. [PDF]

Plant Genome
Castillo MP, Oyebode OG, Talag J, Bunting V, Kaur N, Doran P, Barry K, Competti D, Schmutz J, Schlautman B, Humphries A, Ghamkhar K, Moore V, Rios E, Harkess A, Wolfe M.   +15 more
europepmc   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Additional PAX3 Variants for Dominant Blue Eyes in Cats. [PDF]

Anim Genet
Abitbol M, Eiselé T, Lipovenko E.
europepmc   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Functional analysis of germline RUNX1 variants identified in individuals with suspected familial platelet disorder. [PDF]

Blood Adv
Menezes AC, Deuitch NT, Pintuff A, Zhen T, Wincovitch S, Ozturk K, Carter H, Ripperger T, Godley LA, Liu PP.   +9 more
europepmc   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

The Animal Variant Classification Guidelines v2: An Update With New Criteria and Improved Clarifications. [PDF]

Anim Genet
Desmet L, Ferrari C, Abitbol M, Anderson H, Bannasch D, Bauer H, Bell J, Bilgen N, Chevallier L, Dufaure de Citres C, Donner J, Finno CJ, Giovambattista G, Harrison SM, Hayward JJ, Häggström J, Huff JT, Leeb T, Ljungvall I, Longeri M, Lyons LA, Martinez M, Mellersh C, Nicholas FW, Ohlsson Å, Petersen JL, Smets P, Strillacci MG, Tammen I, Van Buren S, van Steenbeek FG, Broeckx BJG.   +31 more
europepmc   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

ABCB1 Frameshift Deletion in Skye Terriers With Potential Pharmacogenetic Relevance. [PDF]

Anim Genet
Nielsen M, Gredal H, Karlsson Å, Meadows JRS, Arendt M.   +4 more
europepmc   +1 more source

MANAGING THE CORN ROOTWORM VARIANT: EMPIRICAL RESULTS FROM AN INDIANA FARMER SURVEY [PDF]

The emergence of a corn rootworm "variant" has reduced the effectiveness of a corn-soybean rotation in some areas of Indiana. This research identifies potential control alternatives.
Martin, Marshall A., Harbor, Anetra L.
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