Results 21 to 30 of about 145,652 (224)

The emergence of property rights enforcement in early trade : A behavioral model without reputational effects [PDF]

, 2008
Original article can be found at: http://www.sciencedirect.com/ Copyright ElsevierThe present article focuses on the conditions that allow governments to increase property rights protection because they expect enough income from such action. We develop a
Hodgson, G.M., Knudsen, T.
core   +5 more sources

Totally positive refinable functions with general dilation M [PDF]

, 2017
We construct a new class of approximating functions that are M-refinable and provide shape preserving approximations. The refinable functions in the class are smooth, compactly supported, centrally symmetric and totally positive.
GORI, Laura, PITOLLI, Francesca
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Geometrically Designed Variable Knot Splines in Generalized (Non-)Linear Models [PDF]

, 2017
In this paper we extend the GeDS methodology, recently developed by Kaishev et al. (2016) for the Normal univariate spline regression case, to the more general GNM (GLM) context.
Dimitrova, D. S., Kaishev, V. K., Lattuada, L., Verrall, R. J.   +3 more
core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

An Advection Scheme using Paired Explicit Runge-Kutta Time Integration for Atmospheric Modeling

Gaoyuan qixiang
In this paper， a new numerical scheme was proposed to solve the advection equation in a multi-moment nonhydrostatic dynamical core.To guarantee the shape-preserving property， the limiting operations are devised for a hybrid discretization framework ...
Zhaoyang SUN, Chungang CHEN, Xingliang LI, Xueshun SHEN   +3 more
doaj   +1 more source

Implicit and Implicit-Explicit Strong Stability Preserving Runge-Kutta Methods with High Linear Order

, 2017
When evolving in time the solution of a hyperbolic partial differential equation, it is often desirable to use high order strong stability preserving (SSP) time discretizations. These time discretizations preserve the monotonicity properties satisfied by
Conde, Sidafa, Gottlieb, Sigal, Grant, Zachary J., Shadid, John N.   +3 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

DStreaM: A Convective Term Approximation Approach That Corresponds to Pure Convection

Mathematics
In recent decades, considerable effort has been devoted to developing higher-order schemes for the discretization of convective terms that are both stable and reliable.
Kiril Shterev
doaj   +1 more source