Results 141 to 150 of about 4,172,585 (318)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

De rol van codewisseling in conversaties, zowel in gesproken taal als in gesprekken op internet.

open access: yes, 2016
In onderzoek naar codewisseling waren conversationele aspecten lange tijd ondergeschikt aan grammaticale analyses. Werk van o.a. Auer heeft daar verandering in gebracht. In dit artikel wordt ingegaan op de manier van analyseren die Auer voorstelt in zijn
Nortier, J.M.   +2 more
core  

Critical appraisal and meta-analysis of biological variation studies on glycosylated albumin, glucose and HbA1c

open access: yesAdvances in Laboratory Medicine, 2020
Ricós Carmen   +15 more
doaj   +1 more source

Grain-size, coarse fraction lithology and clay mineral compositions of surface sediments from Ross Sea, Antarctica: implications for their provenance and delivery mode

open access: yesFrontiers in Marine Science
Knowledge on spatial distribution, provenance and delivery mode of surface sediment aids in interpretation of nearby sediment records for paleoenvironmental reconstruction.
Li Wu   +12 more
doaj   +1 more source

Variational Tempering

open access: yes, 2014
published version, 8 pages, 4 ...
Stephan Mandt   +4 more
openaire   +3 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Assessment of the global ocean heat content and North Atlantic heat transport over 1993–2020

open access: yesnpj Climate and Atmospheric Science
Understanding changes in global ocean heat content (OHC) is essential for investigating Earth’s energy imbalance and climate change. OHC trends are assessed using four state-of-the-art ocean reanalyses and one objective analysis.
Chunlei Liu   +15 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Harmful Microalgae Exhibit Broad Environmental Adaptability in High‐Salinity Area Across the Dafengjiang River Estuary

open access: yesEcology and Evolution
Harmful algal blooms (HABs) often occur in estuaries due to their unique environmental heterogeneity, posing significant environmental and human health risks. However, there is limited understanding of the community composition and community‐level change
Jiongqing Huang   +11 more
doaj   +1 more source

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