Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
The impact of pathological fluctuations versus biological variation on the interpretation of laboratory values. [PDF]
Pract Lab MedOrtiz AM +8 more
europepmc +1 more source
Variation of Galactic Bar Length with Amplitude and Density as Evidence for Bar Growth over a Hubble Time [PDF]
, 2007 Bruce G. Elmegreen +5 more
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Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Top-down pressure and bottom-up responses: a study on provincial Governments' adoption and textual reproduction of sports industry policies in China. [PDF]
Front Sports Act LivingLi Z, Zhou J, Liu J.
europepmc +1 more source
The ecology of sexual conflict: Temperature variation in the social environment can drastically modulate male harm to females [PDF]
, 2019 Roberto García‐Roa +2 more
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Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Interactions of a Forced Vibrating Membrane with a Cylindrical Acoustic Cavity. [PDF]
Sensors (Basel)Gascón-Pérez M.
europepmc +1 more source
Effect of Genetic Variation in a Drosophila Model of Diabetes-Associated Misfolded Human Proinsulin [PDF]
, 2013 Bin He +12 more
openalex +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source