Results 221 to 230 of about 3,271,603 (299)

Effect of Topical Intra-Auricular Lidocaine on Tinnitus: A Randomized Double-Blind Placebo-Controlled Study. [PDF]

Int Arch Otorhinolaryngol
Campos TV, Bento RF, Oticica J, Jabour MS, Távora N, Jardim I, de Marchi CL, Tsuji RK.   +7 more
europepmc   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Changes in internal jugular vein respiratory variation during tidal volume challenge predict volume responsiveness in lumbar surgery under protective ventilation: a prospective cohort study. [PDF]

J Intensive Care
Wu M, Xu J, Liu X, Dong Y, Sun Y, Gu X, Bo J.   +6 more
europepmc   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

Priorities for New Data Collection. [PDF]

Dev Sci
MacWhinney B, Snow C.
europepmc   +1 more source

Variations in Histamine Levels in Guinea Pig Skin Related to Skin Region; Age (or Weight); and Time After Death of the Animal1

, 1956
Herbert H. Johnson
openalex   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Variation in healthcare services utilization and continuity of care in long-term care facilities: a cross-sectional study. [PDF]

BMC Health Serv Res
Schwabe J, Pulling BW, Caughey GE, Crotty M, Williams H, Kellie A, Roder D, Nixon KL, Harvey G, Sluggett JK, Cations M, Gill TK, Khadka J, Corlis M, von Thien M, Inacio MC.   +15 more
europepmc   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Density-dependent recruitment but not survival drives cyclic dynamics in a field vole population. [PDF]

Proc Natl Acad Sci U S A
Lambin X, Begon M, Burthe SJ, Graham IM, MacKinnon JL, Telfer S, Oli MK.   +6 more
europepmc   +1 more source