Results 31 to 40 of about 7,252,224 (344)

An integrated map of genetic variation from 1,092 human genomes

open access: yesNature, 2012
By characterizing the geographic and functional spectrum of human genetic variation, the 1000 Genomes Project aims to build a resource to help to understand the genetic contribution to disease.
Gil A. David M. Richard M. Gonçalo R. David R. Aravind McVean Altshuler (Co-Chair) Durbin (Co-Chair) Abec   +499 more
semanticscholar   +1 more source

Modulated Expression of the Protein Kinase GSK3 in Motor and Dopaminergic Neurons Increases Female Lifespan in Drosophila melanogaster

open access: yesFrontiers in Genetics, 2020
Most eukaryotic genes express multiple transcripts and proteins, and a sophisticated gene expression strategy plays a crucial role in ensuring the cell-specificity of genetic information and the correctness of phenotypes. The Drosophila melanogaster gene
Mikhail V. Trostnikov   +8 more
doaj   +1 more source

A Millennial-Scale Tephra Event-Stratigraphic Record of the South China Sea since the Penultimate Interglacial

open access: yesLithosphere, 2022
Large volcanic eruptions have significant impacts on climate and environmental changes. The deposition of tephra in marine sediments may serve as an eruption recorder, but it has not been extensively studied in the western Pacific.
Weijia Feng   +4 more
doaj   +1 more source

A map of human genome variation from population-scale sequencing

open access: yesNature, 2010
The 1000 Genomes Project aims to provide a deep characterization of human genome sequence variation as a foundation for investigating the relationship between genotype and phenotype.
G. Abecasis   +7 more
semanticscholar   +1 more source

Increasing eutrophication driven by the increase of phosphate discharge in a subtropical bay in the past 30 years

open access: yesFrontiers in Marine Science, 2023
Although great efforts have been made to decrease nutrient (notably nitrogen and phosphorus) loads and lighten related environmental damages, coastal eutrophication remains a persistent environmental crisis.
Guirong He   +12 more
doaj   +1 more source

Differential expression analysis of multifactor RNA-Seq experiments with respect to biological variation

open access: yesNucleic Acids Research, 2012
A flexible statistical framework is developed for the analysis of read counts from RNA-Seq gene expression studies. It provides the ability to analyse complex experiments involving multiple treatment conditions and blocking variables while still taking ...
Davis J. McCarthy   +2 more
semanticscholar   +1 more source

International variation [PDF]

open access: yesOncogene, 2004
There were an estimated 10 million new cases, 6 million deaths and 22 million persons living with cancer in the year 2000. The most common cancers are, in terms of new cases, lung (1.2 million), breast (1.05 million), colon-rectum (945 000), stomach (876 000) and liver (564 000).
openaire   +2 more sources

A Quality Improvement Initiative to Standardize Pneumocystis jirovecii Pneumonia Prophylaxis in Pediatric Patients With Solid Tumors

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric patients with extracranial solid tumors (ST) receiving chemotherapy are at an increased risk for Pneumocystis jirovecii pneumonia (PJP). However, evidence guiding prophylaxis practices in this population is limited. A PJP‐related fatality at our institution highlighted inconsistent prescribing approaches and concerns about
Kriti Kumar   +8 more
wiley   +1 more source

Machine Learning Reconstruction of Wyrtki Jet Seasonal Variability in the Equatorial Indian Ocean

open access: yesAlgorithms
The Wyrtki Jet (WJ), a pivotal surface circulation system in the equatorial Indian Ocean, exerts significant regulatory control over regional climate dynamics through its intense eastward transport characteristics, which modulate water mass exchange ...
Dandan Li   +4 more
doaj   +1 more source

Comparative Analysis of Heavy Metals in Sediments of China's Bays

open access: yesHaiyang Kaifa yu guanli, 2023
With the development of industry, aquaculture and shipping in coastal city, large amounts of heavy metals had been released to the bay and transferred to sediment, the heavy metal pollution of sediment in bay had become a prominent environmental question.
Qinghua HOU   +4 more
doaj  

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