Results 41 to 50 of about 9,552,128 (326)
RAD50 missense variants differentially affect the DNA damage response and mitotic progression
FEBS Letters, EarlyView.RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker +9 more
wiley +1 more source
Canadian Medical Association Journal, 2021 The facility was far uptown. We all dozed off during the long ride, and by the time the train lurched into the station, we were groggy. Though we were not native New Yorkers, three years in the city was enough to develop that uncanny ability to emerge from sleep just before missing your stop ...
openaire +2 more sources
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
'Variation' : 32 short performances [PDF]
, 2008 'Variation' consists of 32 short performances varying in length from 35 seconds to 6 minutes and 4 seconds.
Spencer, Michael
core
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Frontiers in Genetics, 2018 In recent years, several genes involved in complex neuron specification networks have been shown to control life span. However, information on these genes is scattered, and studies to discover new neuronal genes and gene cascades contributing to life ...
Alexander V. Symonenko +5 more
doaj +1 more source
Variation of Hilbert Coefficients [PDF]
, 2012 For a Noetherian local ring $(\RR, \m)$, the first two Hilbert coefficients, $e_0$ and $e_1$, of the $I$-adic filtration of an $\m$-primary ideal $I$ are known to code for properties of $\RR$, of the blowup of $\spec(\RR)$ along $V(I)$, and even of their
Communicated Irena Peeva +5 more
core +1 more source
Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target
FEBS Letters, EarlyView.This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz +5 more
wiley +1 more source
An Improved MG Model for Turbulent Mixing Parameterization in the Northwestern South China Sea
Journal of Marine Science and EngineeringUsing in situ microstructure observations from 2010 to 2018, this study assesses the applicability of turbulent mixing parameterization schemes in the northwestern South China Sea (NSCS) and improves the MG model proposed by MacKinnon and Gregg in 2003 ...
Minghao Hu +5 more
doaj +1 more source
Oberwolfach Reports, 2005 The workshop continued the longstanding biannual series at Oberwolfach on Calculus of Variations. This Oberwolfach series provides an imporant service to the mathematics community, being currently the only periodic international meeting in this very active area.
Gianni Dal Maso +2 more
openaire +2 more sources