Results 91 to 100 of about 29,904 (263)
IEEE Access, 2016 This paper discusses a novel conceptual formulation of the fractional-order Euler-Lagrange equation for the fractional-order variational method, which is based on the fractional-order extremum method. In particular, the reverse incremental optimal search
Yi-Fei Pu
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Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
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Vectorial Ekeland Variational Principles and Inclusion Problems in Cone Quasi-Uniform Spaces
Abstract and Applied Analysis, 2012 Some new vectorial Ekeland variational principles in cone quasi-uniform spaces are proved. Some new equivalent principles, vectorial quasivariational inclusion principle, vectorial quasi-optimization principle, vectorial quasiequilibrium principle are ...
Jiang Zhu +3 more
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Genetic analysis of environmental variation
Genetics Research, 2010 SummaryEnvironmental variation (VE) in a quantitative trait – variation in phenotype that cannot be explained by genetic variation or identifiable genetic differences – can be regarded as being under some degree of genetic control. Such variation may be either between repeated expressions of the same trait within individuals (e.g. for bilateral traits),
Hill, W.G., Mulder, H.A.
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FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
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FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
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Advances in Meteorology, 2018 When the coarse-resolution observations used in the first step of multiscale and multistep variational data assimilation become increasingly nonuniform and/or sparse, the error variance of the first-step analysis tends to have increasingly large spatial ...
Qin Xu, Li Wei
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From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
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Noise-Aware Variational Eigensolvers: A Dissipative Route for Lattice Gauge Theories
PRX QuantumWe propose a novel variational ansatz for the ground-state preparation of the Z_{2} lattice gauge theory (LGT) in quantum simulators. It combines dissipative and unitary operations in a completely deterministic scheme with a circuit depth that does not ...
Jesús Cobos +4 more
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Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
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