Results 41 to 50 of about 823,067 (286)

Nonconforming finite-element discretization of convex variational problems [PDF]

open access: yes, 2010
The Lavrentiev gap phenomenon is a well-known effect in the calculus of variations, related to singularities of minimizers. In its presence, conforming finite-element methods are incapable of reaching the energy minimum.
Ortner, Christoph, C. Ortner
core   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

An adaptive finite element approximation of a variational model of brittle fracture [PDF]

open access: yes, 2010
The energy of the Francfort–Marigo model of brittle fracture can be approximated, in the sense of Gamma-convergence, by the Ambrosio–Tortorelli functional.
Christoph Ortner   +5 more
core   +1 more source

Globally Convergent Variational Inference

open access: yesAdvances in Neural Information Processing Systems 37
Accepted to the 38th Conference on Neural Information Processing Systems (NeurIPS 2024)
Declan McNamara   +2 more
openaire   +4 more sources

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

On three-step iterative schemes associated with general quasi-variational inclusions

open access: yesAlexandria Engineering Journal, 2022
In this paper, we investigate new classes of general quasi-variational inclusions. In this regard, we prove that general quasi-variational inclusions and fixed point problems are equivalent.
Muhammad Aslam Noor   +3 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

A new error estimate on uniform norm of Schwarz algorithm for elliptic quasi-variational inequalities with nonlinear source terms

open access: yesJournal of Inequalities and Applications, 2018
The Schwarz algorithm for a class of elliptic quasi-variational inequalities with nonlinear source terms is studied in this work. The authors prove a new error estimate in uniform norm, making use of a stability property of the discrete solution.
Allaoua Mehri, Samira Saadi
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

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