Results 61 to 70 of about 11,193 (260)

Extended Variational Message Passing for Automated Approximate Bayesian Inference

open access: yesEntropy, 2021
Variational Message Passing (VMP) provides an automatable and efficient algorithmic framework for approximating Bayesian inference in factorized probabilistic models that consist of conjugate exponential family distributions.
Semih Akbayrak   +2 more
doaj   +1 more source

Variational Inference in Nonconjugate Models

open access: yesJ. Mach. Learn. Res., 2012
Mean-field variational methods are widely used for approximate posterior inference in many probabilistic models. In a typical application, mean-field methods approximately compute the posterior with a coordinate-ascent optimization algorithm. When the model is conditionally conjugate, the coordinate updates are easily derived and in closed form ...
Chong Wang 0002, David M. Blei
openaire   +4 more sources

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Speaker-dependent laser Doppler vibrometer–based voice conversion for dysarthric speech under noisy conditions [PDF]

open access: yesJASA Express Letters
This study proposed the integration of a laser Doppler vibrometer sensing with a Variational Inference with adversarial learning for Text-to-Speech–based voice conversion system to enhance automatic speech recognition for individuals with dysarthria in ...
Yu-Chuan Lee   +5 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Explicit Gaussian Variational Approximation for the Poisson Lognormal Mixed Model

open access: yesMathematics, 2022
In recent years, the Poisson lognormal mixed model has been frequently used in modeling count data because it can accommodate both the over-dispersion of the data and the existence of within-subject correlation.
Xiaoping Shi   +2 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Symplectic encoders for physics-constrained variational dynamics inference

open access: yesScientific Reports, 2023
We propose a new variational autoencoder (VAE) with physical constraints capable of learning the dynamics of Multiple Degree of Freedom (MDOF) dynamic systems.
Kiran Bacsa   +4 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

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