Development of Novel Immunoassays for Varicella Zoster Virus (VZV) Vaccine and Preliminary Study on Functional Domain of ORF7 protein [PDF]
水痘-带状疱疹病毒(Varicella-ZosterVirus,VZV)是水痘和带状疱疹的病原体。VZV具有高度传染性,初次感染可引发水痘,并可潜伏于患者背根神经节,在年老或免疫力低下时可能激活导致带状疱疹,具有严重的危害性。接种疫苗是预防VZV感染的有效方式,但目前使用的VZV减毒活疫苗株v-Oka仍具有感染和潜伏人神经系统的能力,安全隐患不容忽视,因此,亟需研制更为安全有效的新型疫苗。高效、精确的免疫分析技术体系是研制新型疫苗的重要基础。VZV是一种基因组约125Kb,拥有70个ORF ...
刘剑
core
Women in space: A review of known physiological adaptations and health perspectives
Abstract Exposure to the spaceflight environment causes adaptations in most human physiological systems, many of which are thought to affect women differently from men. Since only 11.5% of astronauts worldwide have been female, these issues are largely understudied.
Millie Hughes‐Fulford +4 more
wiley +1 more source
Seroprevalence of Antibodies to Varicella-zoster Virus in Madrid (Spain) in the Absence of Vaccination [PDF]
Napoleón Pérez‐Farinós +6 more
openalex +1 more source
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Katharina A. Kälber +3 more
wiley +1 more source
An In Vitro Model of Latency and Reactivation of Varicella Zoster Virus in Human Stem Cell-Derived Neurons [PDF]
Varicella zoster virus (VZV) latency in sensory and autonomic neurons has remained enigmatic and difficult to study, and experimental reactivation has not yet been achieved.
Goldstein, RS +4 more
core +4 more sources
Allotype Analysis to Distinguish the Origin of Varicella-Zoster Virus Immunoglobulin G after Allogeneic Stem Cell Transplantation [PDF]
Rie Yamazaki +18 more
openalex +1 more source
CAR‐T cell therapy in systemic rheumatic diseases and autoimmune disorders. (This figure was created using BioRender.com.) ABSTRACT Chimeric antigen receptor T (CAR‐T) cell therapy, originally developed for hematologic malignancies, has emerged as a transformative candidate for systemic rheumatic diseases and autoimmune disorders (AIDs).
Zhidan Fan, Li Zhang, Haiguo Yu
wiley +1 more source
Cerebral Vasculities Associated with Shingles [PDF]
Shingles is a common manifestation of infection with herpes zoster virus (more correctly varicella-zoster virus) in middle-aged or elderly people. We describe three patients who developed brain stem encephalitis and cerebral vasculitis due to infection ...
CROSBIE, JJ, EDGAR, JDM, HAWKINS, SA
core
Utility of direct immunofluorescence and virus culture for detection of varicella-zoster virus in skin lesions [PDF]
Susan Coffin, Richard L. Hodinka
openalex +1 more source
Unraveling Chronic Pain: From Mechanisms and Risks to Diagnosis and Treatment
Chronic pain arises through distinct molecular pathways categorized into nociceptive, neuropathic, and nociplastic types. Nociceptive pain begins with TRP channel activation in peripheral nociceptors, signaling via Aδ‐ and C‐fibers through the spinal dorsal horn and spinothalamic tracts to the brain, regulated by descending inhibition and involving ...
Xiaofeng Dai +3 more
wiley +1 more source

