Results 61 to 70 of about 44,732 (239)

Membrane‐Permeable Nucleoside T‐1106 Diphosphate and Triphosphate Analogues as Antiviral Pronucleotides

Chemistry – A European Journal, EarlyView.
Favipiravir (T‐705) and the non‐fluorinated counterpart (T‐1106) are antiviral agents that inhibit the RNA‐dependent RNA polymerase (RdRp) of various RNA viruses. The antiviral efficacy of nucleoside analogues is strongly dependent on their intracellular activation by cellular kinases to produce their corresponding triphosphate metabolites (T‐705‐RTP ...
Chris Meier, Duan Li, Leentje Persoons, Graciela Andrei, Robert Snoeck, Dominique Schols, Lieve Naesens, Xiao Jia   +7 more
wiley   +1 more source

Persistent high frequencies of varicella-zoster virus ORF4 protein-specific CD4+ T cells after primary infection [PDF]

, 2006
Open reading frame 4 (ORF4) of varicella-zoster virus (VZV) encodes an immediate-early protein that is believed to be important for viral infectivity and establishing latency.
Jones, Louise, Malavige, Gathsaurie N., Ogg, Graham S., Black, Antony P.   +3 more
core   +1 more source

Contemporaneous varicella and zoster or disseminated zoster? A diagnostic challenge in an HIV-positive child

Southern African Journal of Infectious Diseases
Primary infection with Varicella-Zoster virus causes varicella (chickenpox). Thereafter, following reactivation after a period of latency, it can cause zoster (shingles).
Wendy Batyi, Tshepile Tlali, Preethi John, Matilda Mphahlele   +3 more
doaj   +1 more source

Ultrasound‐Guided Liposomal vs. Conventional Bupivacaine Erector Spinae Plane Block Plus Gabapentin for Postherpetic Neuralgia

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study aimed to compare efficacy and safety of ultrasound‐guided erector spinae plane block (ESPB) using liposomal (LB) versus conventional bupivacaine (CB), each plus standardized gabapentin, in patients with postherpetic neuralgia (PHN). A total of 116 PHN patients were randomized to ESPB‐LB or ESPB‐CB; both groups received standardized ...
Xia‐Jing Xu, Li‐Juan Liu, Fa‐Ming Xu, Xiang‐Yu Fang   +3 more
wiley   +1 more source

Characterisation of immune responses to varicella vaccination in relation to clinical outcome [PDF]

, 2010
PhDThis thesis examines both humoral and cellular adaptive immune responses to varicella vaccination (up to 18 months post immunisation), in an ethnically diverse population of healthcare workers.
McDonald, Suzanna Leonie Rose
core  

Early Remission of Cerebrospinal Fluid Interleukin‐6 After Initial Immunotherapy Predicts a Good Prognosis in Autoimmune Encephalitis

Neurology and Clinical Neuroscience, EarlyView.
ABSTRACT Background Autoimmune encephalitis therapy requires adjusting the regimen based on therapeutic response; however, clinical indicators of this response remain unknown. Aim To determine the predictive capability of cerebrospinal fluid (CSF), electroencephalography (EEG), and brain magnetic resonance imaging (MRI) in identifying responders to ...
Yuta Madokoro, Yuto Uchida, Hiroyasu Inoue, Toyohiro Sato, Teppei Fujioka, Masayuki Mizuno, Shoji Kawashima, Masahiro Oomura, Noriyuki Matsukawa   +8 more
wiley   +1 more source

Case Report: Various Clinical Manifestations Caused by Varicella-Zoster Virus in a Family

Frontiers in Pediatrics, 2022
A family cluster of varicella-zoster virus (VZV) infections was reported. Four family members (two children and their parents) continuously develop varicella after the grandmother’s herpes zoster.
Qinghong Meng, Bingsong Wang, Xianlai Zhang, Zhen Li, Wenjie Wang, Kaihu Yao   +5 more
doaj   +1 more source

Vírus varicela zoster em paralisia de Bell: estudo prospectivo Varicella zoster virus in Bell's palsy: a prospective study

Brazilian Journal of Otorhinolaryngology, 2010
Embora a paralisia de Bell seja o tipo mais frequente de paralisia facial periférica,sua causa ainda é objeto de inúmeros questionamentos. A reativação do vírus varicela zoster tem sido considerada uma das principais causas da paralisia de Bell, porém ...
Mônica Alcantara de Oliveira Santos, Hélio H Caiaffa Filho, Melissa Ferreira Vianna, Andressa Guimarães do Prado Almeida, Paulo Roberto Lazarini   +4 more
doaj   +1 more source

Effectiveness of Amenamevir Vs. Valacyclovir in Preventing Herpes Zoster‐Related Hospitalization and Complications: A Target Trial Emulation Using a Large Japanese Claims Database

The Journal of Dermatology, EarlyView.
ABSTRACT Amenamevir is a novel anti‐herpes zoster drug that is increasingly used in Japan because of its once‐daily administration and lack of renal dose adjustment requirements. However, evidence of its clinical effectiveness is limited. This study aimed to estimate the clinical effectiveness of amenamevir vs. valacyclovir in preventing zoster‐related
Yasuhiro Kano, Yuya Kimura, Hideo Yasunaga   +2 more
wiley   +1 more source

Varicella Zoster Virus Vasculopathies [PDF]

, 2008
The clinical, CSF, imaging, and virological features of varicella zoster virus (VZV) vasculopathies in 30 patients (7 children) are reviewed by researchers at various centers in the US and ...
J Gordon Millichap
core   +1 more source