Results 101 to 110 of about 60,759 (242)
Development of Novel Immunoassays for Varicella Zoster Virus (VZV) Vaccine and Preliminary Study on Functional Domain of ORF7 protein [PDF]
, 2016 水痘-带状疱疹病毒(Varicella-ZosterVirus，VZV)是水痘和带状疱疹的病原体。VZV具有高度传染性，初次感染可引发水痘，并可潜伏于患者背根神经节，在年老或免疫力低下时可能激活导致带状疱疹，具有严重的危害性。接种疫苗是预防VZV感染的有效方式，但目前使用的VZV减毒活疫苗株v-Oka仍具有感染和潜伏人神经系统的能力，安全隐患不容忽视，因此，亟需研制更为安全有效的新型疫苗。高效、精确的免疫分析技术体系是研制新型疫苗的重要基础。VZV是一种基因组约125Kb，拥有70个ORF ...
刘剑
core
An In Vitro Model of Latency and Reactivation of Varicella Zoster Virus in Human Stem Cell-Derived Neurons [PDF]
, 2015 Varicella zoster virus (VZV) latency in sensory and autonomic neurons has remained enigmatic and difficult to study, and experimental reactivation has not yet been achieved.
Goldstein, RS +4 more
core +4 more sources
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Katharina A. Kälber +3 more
wiley +1 more source
MedComm, Volume 7, Issue 4, April 2026.CAR‐T cell therapy in systemic rheumatic diseases and autoimmune disorders. (This figure was created using BioRender.com.) ABSTRACT Chimeric antigen receptor T (CAR‐T) cell therapy, originally developed for hematologic malignancies, has emerged as a transformative candidate for systemic rheumatic diseases and autoimmune disorders (AIDs).
Zhidan Fan, Li Zhang, Haiguo Yu
wiley +1 more source
Revista da Sociedade Brasileira de Medicina TropicalWe report a case of encephalitis associated with Zika virus infection and reactivation of varicella-zoster virus in the central nervous system of a Brazilian child.
Marcelo Adriano da Cunha e Silva Vieira +10 more
doaj +1 more source
DNA Virus Detection in Olfactory Neuroblastomas Using Targeted Enrichment NGS
Neuropathology, Volume 46, Issue 2, April 2026.ABSTRACT A variety of malignancies can be found in the sinonasal tract including the nasal cavity, paranasal sinuses, and skull base. Many of these are attributed to viruses, for example, carcinomas with the presence of transcriptionally active high‐risk human papillomavirus, as well as Epstein–Barr virus associated malignant lymphoepithelial carcinoma
Maria K. Jauhiainen +7 more
wiley +1 more source
Cerebral Vasculities Associated with Shingles [PDF]
, 1990 Shingles is a common manifestation of infection with herpes zoster virus (more correctly varicella-zoster virus) in middle-aged or elderly people. We describe three patients who developed brain stem encephalitis and cerebral vasculitis due to infection ...
CROSBIE, JJ, EDGAR, JDM, HAWKINS, SA
core
Advanced Science, Volume 13, Issue 14, 9 March 2026.This study designs a novel mRNA‐LNP vaccine targeting VZV glycoprotein E (gE) for herpes zoster via an AI‐assisted pipeline. Validated in mice and rhesus macaques, the mRNA‐LNP vaccine shows strong humoral and cellular immune responses, with CD4+ T‐cell responses more effective and durable than Shingrix, offering a promising prophylactic option ...
Kai Dong +6 more
wiley +1 more source
DiseasesBackground: The varicella-zoster virus is a highly contagious human herpesvirus that primarily causes varicella (chickenpox) as an initial infection, targeting T cells, neurons, as well as skin cells, and can later reactivate to cause herpes zoster ...
Michał Oleszko +3 more
doaj +1 more source
Varicella and Herpes Zoster in Madrid, based on the Sentinel General Practitioner Network: 1997–2004
BMC Infectious Diseases, 2007 Background Varicella (chickenpox) is the primary disease caused by varicella-zoster virus. It is extremely contagious and is frequent in children. Indeed, in the absence of vaccination, a high proportion of the population is liable to contract it. Herpes
Gutiérrez-Rodríguez Ángeles +8 more
doaj +1 more source