Results 61 to 70 of about 42,159 (230)
Infections in Chronic Lymphocytic Leukemia: Evolving Risks and Prevention Strategies
ABSTRACT Infections remain a leading cause of morbidity and mortality in patients with chronic lymphocytic leukemia (CLL), reflecting both intrinsic immune dysfunction and therapy‐related immunosuppression. The pathogenesis of immunodeficiency in CLL is multifactorial: neoplastic B cells impair humoral immunity, T cells are functionally exhausted, and ...
Enrica Antonia Martino +10 more
wiley +1 more source
Abstract The etiology of Alzheimer's disease (AD) remains under active debate. In this perspective, we explore the hypothesis that a primarily infection‐caused chronic dysregulation and weakening of human innate immunity via the underexpression, degradation, and inactivation of innate immune proteins necessary for direct antimicrobial effects and ...
Annelise E. Barron +3 more
wiley +1 more source
A rare neurological sequelae of chicken pox in an adult
Chicken pox is a disease of childhood caused by varicella zoster virus belonging to the α-herpesvirus-3 family. But the clinical presentation in adults is uncommon and is usually associated with complications.
Kandan Balamurugesan +3 more
doaj +1 more source
ABSTRACT This case highlights a relapse of major depressive disorder in an elderly man following a flu‐like illness, with clinical features and laboratory findings supporting a possible inflammatory contribution. It emphasises the relevance of the inflammatory theory of depression, especially in individuals with late‐life depression and recent immune ...
Nauman Malik, Mohamed A. Mohamed
wiley +1 more source
Biologics to Treat Atopic Dermatitis: Effectiveness, Safety, and Future Directions
ABSTRACT Atopic dermatitis (AD) is one of the most common chronic inflammatory skin diseases worldwide. The clinical presentation of AD is heterogeneous and is characterized by a relapsing and remitting course. Most patients suffer from mild AD while approximately 5% to 20% experience severe disease activity, which often requires systemic treatment ...
Marjolein S. de Bruin‐Weller +9 more
wiley +1 more source
Antiviral Targeting of Varicella Zoster Virus Replication and Neuronal Reactivation Using CRISPR/Cas9 Cleavage of the Duplicated Open Reading Frames 62/71 [PDF]
Betty W. Wu +3 more
openalex +1 more source
EPID-17. ANTIBODY REACTIVITY TO VARICELLA ZOSTER VIRUS IS ASSOCIATED WITH IMPROVED GLIOMA SURVIVAL AND IS MODIFIED BY GERMLINE HLA POLYMORPHISMS [PDF]
Stephen Francis +4 more
openalex +1 more source
Vaccination Recommendations in Patients With Atopic Dermatitis Treated With JAK Inhibitors
Inmunization and Screening Protocol for the Safe Initiation of JAK Inhibitors. ABSTRACT Atopic dermatitis therapy has undergone a revolutionary change with the introduction of Janus kinase (JAK) inhibitors. Despite their general safety profile, these immunomodulatory drugs require special precautions with respect to infection risk and vaccine ...
Mariano Ara‐Martín +5 more
wiley +1 more source
Ischemic Stroke in Hypereosinophilic Syndrome: A Clinicopathologic Study of Two Cases
ABSTRACT Ischemic stroke is a rare complication of hypereosinophilic syndrome (HES). Manifestations of stroke in HES have been described in the radiologic literature; however the pathologic characterization of central nervous system (CNS) involvement in HES is limited.
Karina C. Martin +3 more
wiley +1 more source

