Results 61 to 70 of about 63,000 (292)
ABSTRACT The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its ...
Dayanna Isabel Araque Gelves+3 more
wiley +1 more source
Background Varicella zoster virus (VZV) causes varicella primarily in childhood, and some rare adults also report varicella. Herpes zoster mainly occurs in adults by endogenous reactivation of latent VZV.
Guangcheng Xie+6 more
doaj +1 more source
Varicella-zoster virus (VZV) causes varicella in primary infection and zoster after reactivation from latency. Both herpes simplex virus (HSV) and VZV are classified into the same alpha-herpesvirus subfamily. Although most VZV genes have their HSV homologs, VZV has many unique biological characteristics.
Kyosuke Kanai+2 more
openaire +3 more sources
Populations Addressed in Vaccines Approved via the European Medicines Agency
Therapeutic and prophylactic agents require robust evidence before patient use. Randomized controlled trials are essential for evaluating safety and efficacy but often exclude specific populations that are also targets for the intervention. This study assessed which populations are included in vaccine registration studies and/or addressed in label ...
Débora D. Gräf+3 more
wiley +1 more source
Varicella zoster virus lies dormant in the dorsal root ganglia after symptomatic chicken pox infection, usually in childhood. If the virus reactivates in the trigeminal ganglia, it can cause varicella zoster ophthalmicus, which can have severe ocular ...
Helene Jensen+4 more
doaj +1 more source
Immunizations - Not Just for Kids [PDF]
Immunizations/vaccinations are beneficial for most people of all ages. Yet the mistaken belief persists that, with the exception of the flu vaccine, children should be the primary recipients of this important area of primary disease prevention.
Harrison G. Bloom
core
Deep Sequencing of Distinct Preparations of the Live Attenuated Varicella-Zoster Virus Vaccine Reveals a Conserved Core of Attenuating Single-Nucleotide Polymorphisms [PDF]
The continued success of the live attenuated varicella-zoster virus vaccine in preventing varicella-zoster and herpes zoster is well documented, as are many of the mutations that contribute to the attenuation of the vOka virus for replication in skin. At
Breuer, J+4 more
core +1 more source
Exploring the Potential and Advancements of Circular RNA Therapeutics
Given the remarkable advantages in terms of stability, sustained expression profile, safety, wide range of druggable targets, scalable and cost‐effective manufacturing capabilities, circRNA is currently undergoing intensive investigation for various therapeutic applications such as vaccines, protein replacement, genetic disease treatment, gene therapy,
Lei Wang+6 more
wiley +1 more source
Theories on Varicella Zoster Virus Reactivation Based on Shingles Patterns [PDF]
Herpes zoster, a disease also known as shingles or as zoster, infects the sensory nerve ganglion and the peripheral nerve and its branches, resulting in pain to the affected dermatomes.
Nussbaum, Ralph
core +1 more source
This case report describes a 24‐year‐old woman with trisomy 21 and an incomplete childhood vaccination history who developed severe disseminated varicella and varicella pneumonia. Chest CT on admission day 3 revealed scattered small nodules in both lung fields, characteristic of varicella pneumonia.
Satoshi Inaba+3 more
wiley +1 more source